Department of Dermatology, Edouard Herriot Hospital Group, Hospices Civils de Lyon, Lyon, France.
Transpl Int. 2010 Oct;23(10):e62-4. doi: 10.1111/j.1432-2277.2010.01147.x.
Orf is a viral skin infection due to a poxvirus. It manifests as a nodule of the hands that heals spontaneously within 3-4 weeks, but may be persisting and difficult to treat in immunocompromised patients. Very few cases have been reported in transplant patients; therefore, management is not established. We report a renal transplant recipient with a rapidly growing orf which regressed after application of imiquimod and a reduction in immunosuppression without damage on his renal function. This case suggests that a rapidly growing orf in transplant patients behaves as an opportunistic infection and therefore minimization should be considered along with a topical treatment.
羊痘是一种由痘病毒引起的病毒性皮肤感染。它表现为手部结节，在 3-4 周内会自行愈合，但在免疫功能低下的患者中可能持续存在且难以治疗。在移植患者中很少有病例报道；因此，其治疗方法尚未建立。我们报告了一例肾移植受者，其 rapidly growing orf 在应用咪喹莫特和减少免疫抑制后消退，肾功能未受损。该病例提示，移植患者的 rapidly growing orf 表现为机会性感染，因此应考虑最小化治疗，并进行局部治疗。
