一名淋巴瘤患者的进行性开放阅读框病毒感染：使用咪喹莫特成功治疗

Progressive ORF virus infection in a patient with lymphoma: successful treatment using imiquimod.

作者信息

Lederman Edith R, Green Gary M, DeGroot Henry E, Dahl Patricia, Goldman Erinn, Greer Patricia W, Li Yu, Zhao Hui, Paddock Christopher D, Damon Inger K

机构信息

Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.

出版信息

Clin Infect Dis. 2007 Jun 1;44(11):e100-3. doi: 10.1086/517509. Epub 2007 Apr 19.

DOI:10.1086/517509

PMID:17479930

Abstract

Orf virus is a parapoxvirus that infects small ruminants worldwide. We present the case report of a 73-year-old woman with non-Hodgkins lymphoma who developed progressive orf virus lesions that were unresponsive to surgical debridement and to cidofovir therapy. The patient's orf virus infection was successfully treated with topical imiquimod despite progression of her malignancy.

摘要

羊痘病毒是一种副痘病毒，可感染全球范围内的小型反刍动物。我们报告一例73岁非霍奇金淋巴瘤女性患者，其出现进行性羊痘病毒皮损，对手术清创和西多福韦治疗均无反应。尽管患者恶性肿瘤进展，但局部应用咪喹莫特成功治愈了其羊痘病毒感染。