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重新审视爬行动物和两栖动物的代谢性骨病

A fresh look at metabolic bone diseases in reptiles and amphibians.

作者信息

Klaphake Eric

机构信息

Animal Medical Center, 216 North 8th Avenue, Bozeman, MT 59715, USA.

出版信息

Vet Clin North Am Exot Anim Pract. 2010 Sep;13(3):375-92. doi: 10.1016/j.cvex.2010.05.007.

DOI:10.1016/j.cvex.2010.05.007
PMID:20682425
Abstract

Metabolic bone diseases (MBDs) are a common presenting complaint in reptiles and amphibians to veterinarians; however, understanding of the causes and diagnostic and treatment options is often extrapolated from human or other mammalian medicine models. Although the roles of UV-B, calcium, phosphorus, and cholecalciferol are better understood in some MBDs, there remain many X factors that are not. Likewise, quantitative diagnosis of MBDs has been difficult not only in terms of staging a disease but also regarding whether or not a condition is present. Treatment options also present challenges in corrective husbandry and diet modifications, medication/modality selection, and dosing/regimen parameters.

摘要

代谢性骨病(MBDs)是爬行动物和两栖动物向兽医常见的就诊主诉;然而,对其病因以及诊断和治疗选择的理解往往是从人类或其他哺乳动物医学模型推断而来的。尽管在某些代谢性骨病中,紫外线B、钙、磷和胆钙化醇的作用已得到更好的理解,但仍有许多未知因素。同样,代谢性骨病的定量诊断不仅在疾病分期方面困难,而且在确定是否存在某种病症方面也很困难。治疗选择在纠正饲养管理和饮食调整、药物/治疗方式选择以及给药/治疗方案参数方面也存在挑战。

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