帕金森病中的移植诱导运动障碍：这是怎么回事？
Graft-induced dyskinesias in Parkinson's disease: what is it all about?
机构信息
Brain Repair Centre and Department of Neurology, University of Cambridge, Cambridge CB2 0PY, UK.
出版信息
Cell Stem Cell. 2010 Aug 6;7(2):148-9. doi: 10.1016/j.stem.2010.07.003.
PMID:20682443
Abstract
The treatment of Parkinson's disease with grafts of fetal ventral mesencephalic tissue has shown some success, but can result in graft-induced dyskinesias (GIDs). Recently in Science Translational Medicine, Politis et al. (2010) demonstrate that GIDs may originate from serotoninergic neurons that are cografted in these transplants.
摘要
用胎儿腹侧中脑组织移植物治疗帕金森病已取得一些成效，但可能导致移植物诱导性运动障碍（GIDs）。最近，Politis 等人（2010 年）在《科学转化医学》上证明，GIDs 可能起源于这些移植中共同植入的血清素能神经元。
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