Department of Medicine, Royal Marsden Hospital, Downs Road, Sutton, Surrey, SM2 5PT, U.K.
Anticancer Res. 2010 Jul;30(7):3015-8.
The examination of limited, potentially non-representative fragments of tumour tissue from a core biopsy can be misleading and misdirect subsequent treatment, especially in cases where a primary tumour has not been identified. This case report is of a 65-year-old woman presenting with a destructive sacral mass, diagnosed on radiological imaging and core biopsy as a hindgut neuroendocrine tumour, which on histopathological review of the subsequently resected tumour was found instead to represent a metastasis from an occult hormone-positive breast cancer with neuroendocrine features.
从核心活检中检查有限的、可能非代表性的肿瘤组织碎片可能会产生误导，并导致随后的治疗方向出现偏差，特别是在尚未确定原发性肿瘤的情况下。本病例报告介绍了一位 65 岁女性，因骶骨破坏性肿块就诊，影像学检查和核心活检诊断为下消化道神经内分泌肿瘤，但对随后切除的肿瘤进行组织病理学检查后发现，其实际上是一种隐匿性激素阳性乳腺癌伴神经内分泌特征的转移灶。
