Accident and Emergency Department, Tuen Mun Hospital, Hong Kong.
Hong Kong Med J. 2010 Aug;16(4):246-51.
To investigate the prevalence and characteristics of abusive drug exposure among non-fatal motor vehicle driver casualties presenting to a designated trauma centre in Hong Kong.
Cross-sectional study.
Designated trauma centre/regional accident and emergency department in Hong Kong.
Non-fatal motor vehicle driver casualties who presented to the trauma centre from 1 January 2007 to 31 December 2007.
Screening of abusive drug exposure using commercial bedside urine immunoassay kits.
Drug screening was performed in 395 injured drivers, 10% of whom tested positive for the drugs of interest. Ketamine was the most commonly detected abusive substance (found in 45% of the subjects). A significantly higher proportion of young drivers (aged <25 years) screened positive (odds ratio=2.3; 95% confidence interval, 1.0-5.2; P=0.04), with the rate being 21%. The presence of these drugs in urine was related to the time of occurrence of the crash; those occurring between midnight and dawn revealed a trend towards a higher proportion of casualties testing drug-positive (odds ratio=2.2; 95% confidence interval, 0.9-5.3; P=0.07). There were no significant differences in the frequency of persons testing positive for the screened drugs with respect to gender, class of motor vehicle driven, or the day of the week on which the crash occurred.
The prevalence of drugged driving among non-fatal casualties in our series of Hong Kong drivers was 10%. The frequency of such drivers testing positive for drugs was significantly higher in persons aged less than 25 years. These findings indicate a need to amend existing laws and implement on-site drug screening for suspected drugged drivers.
调查在香港一家指定创伤中心就诊的非致命性机动车驾驶员伤亡者中滥用药物暴露的流行率和特征。
横断面研究。
香港指定创伤中心/区域急症室。
2007 年 1 月 1 日至 2007 年 12 月 31 日期间到创伤中心就诊的非致命性机动车驾驶员伤亡者。
使用商业床边尿液免疫测定试剂盒筛查滥用药物暴露情况。
对 395 名受伤驾驶员进行了药物筛查,其中 10%的驾驶员检测出有目标药物。氯胺酮是最常检测到的滥用物质(在 45%的受试者中发现)。年轻驾驶员(年龄<25 岁)筛查阳性的比例显著更高(比值比=2.3;95%置信区间,1.0-5.2;P=0.04),为 21%。尿液中存在这些药物与事故发生时间有关;午夜至黎明期间发生的事故中,药物检测阳性的伤亡者比例呈上升趋势(比值比=2.2;95%置信区间,0.9-5.3;P=0.07)。筛查药物阳性的人员性别、驾驶车辆类型或事故发生日等方面的频率无显著差异。
在我们的香港驾驶员系列非致命性伤亡者中,药物驾驶的流行率为 10%。年龄<25 岁的驾驶员中,药物检测阳性的频率显著更高。这些发现表明需要修订现有法律,并对疑似药物驾驶的驾驶员实施现场药物筛查。