线粒体肌病的眼球运动障碍。
Brow motility in mitochondrial myopathy.
机构信息
Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery, School of Medicine of Ribeirão Preto, University of São Paulo, Bandeirantes, Ribeirão Preto, SP, Brasil.
出版信息
Ophthalmic Plast Reconstr Surg. 2010 Nov-Dec;26(6):416-9. doi: 10.1097/IOP.0b013e3181cb57a7.
PURPOSE
To quantify the range of brow excursion in patients with mitochondrial myopathy and chronic progressive external ophthalmoplegia (CPEO).
METHODS
Comparative case series. Digital image processing techniques were used to quantify the upper eyelid resting position, brow excursion, and monocular eye movements (ductions) in 19 patients with mitochondrial myopathy and CPEO and in 27 healthy control subjects.
RESULTS
All patients with CPEO had ptosis ranging from 0.6 to 8 mm. For most patients, eye motility limitation was symmetrical. Elevation was the most affected eye movement. Patient's brow motility was on average 56.7% of the motility seen in the control group, and did not correlate with age or eye motility in any direction. Seventy-six percent of the brows displayed more than 2 mm of excursion.
CONCLUSIONS
In patients with CPEO, the occipitofrontalis muscle is less affected than the extraocular muscles. Most patients display a useful degree of brow excursion that theoretically can be used to clear the visual axis after a conservative brow suspension.
目的
定量分析线粒体肌病伴慢性进行性眼外肌麻痹（CPEO）患者的眉弓运动范围。
方法
对比病例系列研究。使用数字图像处理技术，对 19 例线粒体肌病伴 CPEO 患者和 27 名健康对照者的上睑休息位置、眉弓运动幅度和单眼运动（上、下、内、外转）进行定量分析。
结果
所有 CPEO 患者均有 0.6 至 8mm 的上睑下垂。大多数患者的眼球运动受限是对称的。上抬运动是最受影响的眼球运动。患者的眉弓运动幅度平均为对照组的 56.7%，与任何方向的年龄或眼球运动均无相关性。76%的眉弓运动幅度超过 2mm。
结论
在 CPEO 患者中，额肌比眼外肌受影响小。大多数患者的眉弓运动幅度较大，理论上可以在进行保守性眉弓悬吊后清除视轴。
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