Shen Qian, Yao Yinan, Teng Xiaodong, Zhou Jianying
Department of Respiratory Medicine, The First Affiliated Hospital, College of Medicine, Zhejiang University, Zhejang, PR China.
Intern Med. 2010;49(15):1613-5. doi: 10.2169/internalmedicine.49.3622. Epub 2010 Aug 2.
Endobronchial metastasis from prostate cancer is a rare neoplasm which metastasizes to the proximal central or subsegmental bronchus, in a bronchoscopically visible range. We present a 72-year-old man with a left superior lobar bronchus mass, intrapulmonary metastases, and bone metastases, mimicking primary lung bronchogenic carcinoma. Increasing tPSA, decreasing fPSA/tPSA level, and prostatic puncture pathology proved prostate cancer. Pathomorphology and immunohistochemistry of the mucosa specimen with P504S, PSA revealed the diagnosis of pulmonary metastases from prostate cancer. The patient was treated by hormonal treatment and chemotherapy. He was in remission thirteen months after diagnosis.
前列腺癌的支气管内转移是一种罕见的肿瘤,它转移至近端中央或亚段支气管,在支气管镜可见范围内。我们报告一名72岁男性,其左上叶支气管有肿物,伴有肺内转移和骨转移,酷似原发性肺支气管癌。总前列腺特异性抗原(tPSA)升高、游离前列腺特异性抗原与总前列腺特异性抗原比值(fPSA/tPSA)降低以及前列腺穿刺病理证实为前列腺癌。对黏膜标本进行P504S、前列腺特异性抗原(PSA)的病理形态学和免疫组化检查确诊为前列腺癌肺转移。该患者接受了激素治疗和化疗。诊断后13个月病情缓解。