Transplantation. 2010 Nov 27;90(10):1043-7. doi: 10.1097/TP.0b013e3181efcfe9.
Both innate and adaptive immune cells are actively involved in the initiation and destruction of allotransplants, and there is a true need now to look beyond T cells in the allograft response, examining various non-T-cell types in transplant models and how such cell types interact with T cells in determining the fate of an allograft. Studies in this area may lead to further improvement in transplant outcomes.
先天免疫和适应性免疫细胞都积极参与同种异体移植物的启动和破坏,现在确实需要超越移植物反应中的 T 细胞,在移植模型中检查各种非 T 细胞类型,以及这些细胞类型如何与 T 细胞相互作用以决定同种异体移植物的命运。该领域的研究可能会进一步改善移植结果。