Coelho Liana, Chaves Edna, Vasconcelos Silvânia, Fonteles Marta, De Sousa Francisca, Viana Glauce
Serviço de Farmacologia, Universidade Federal do Ceará (UFC), Brasil.
Acta Med Port. 2010 Jul-Aug;23(4):689-96. Epub 2010 Jul 30.
The attention deficit hyperactivity disorder (ADHD) is usually associated to child development, presenting a strong neurobiological influence and being, thus, mostly common in childhood. This disorder is characterized by a persistent pattern of lack of attention and/or by hyperactivity and impulsivity.
To conduct a systematic literature review on ADHD in children, focusing neurobiological aspects, diagnosis and therapeutic approaches.
This is a literature review about ADHD in childhood, from 1994 through 2008. The neurobiological mechanisms that participate in ADHD are complex, involving the dopaminergic, noradrenergic and serotonergic systems. The diagnosis of ADHD must be based on the clinical behavior, since there is no biological marker defined. Metilfenidate is the main drug used for children's treatment.
The search for relief of ADHD symptoms ought to be based on organic treatments, other specific treatments using medications or neurofeedbacks, as well as behavior therapies.
注意力缺陷多动障碍(ADHD)通常与儿童发育相关,具有强大的神经生物学影响,因此在儿童期最为常见。这种障碍的特征是持续存在注意力不集中和/或多动及冲动行为模式。
对儿童ADHD进行系统的文献综述,重点关注神经生物学方面、诊断和治疗方法。
这是一篇关于1994年至2008年儿童期ADHD的文献综述。参与ADHD的神经生物学机制很复杂,涉及多巴胺能、去甲肾上腺素能和5-羟色胺能系统。由于尚未确定生物学标志物,ADHD的诊断必须基于临床行为。哌甲酯是用于儿童治疗的主要药物。
缓解ADHD症状的探索应基于有机治疗、使用药物或神经反馈的其他特定治疗以及行为疗法。