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癫痫样发作揭示神经囊尾蚴病:加蓬利伯维尔两例临床病例报告

Epileptiform seizures revealing neurocysticercosis: report of two clinical cases in Libreville, Gabon.

作者信息

Okome-Nkoumou M M L, Ondounda M, Dzeing-Ella A, Mounguengui D, Madjinou M I Nziengui, Clevenbergh Ph, Magne C, Nzenze J R

机构信息

Département des Maladies Infectieuses, Faculté de Médecine de Libreville, BP 212, Libreville, Gabon.

出版信息

Trop Doct. 2010 Oct;40(4):235-7. doi: 10.1258/td.2010.090493. Epub 2010 Aug 5.

DOI:10.1258/td.2010.090493
PMID:20688973
Abstract

Neurocysticercosis (NCC) is the most common helminth infection of the central nervous system. It is caused by the larval form of the tapeworm Taenia solium and is increasingly recognized as a major cause of neurologic disease worldwide. Epilepsy is the usual mode of revelation. Neuroimaging, including computed tomography and magnetic resonance imaging, combined with serodiagnostic techniques have led to this increased recognition. We report on two cases (one co-infected with the HIV) of NCC diagnosed in 2006 and 2008 at the Omar Bongo Ondimba Army Teaching Hospital. New-onset epilepsy revealed the two cases. Medical treatment with albendazole, anti-epileptic drugs and corticosteroids led to full recovery. NCC should be considered in tropical countries as a leading cause of epilepsy. Moreover, NCC should be included in the differential diagnosis of neurologic infections in HIV patients in endemic populations.

摘要

神经囊尾蚴病(NCC)是中枢神经系统最常见的蠕虫感染。它由绦虫猪带绦虫的幼虫形式引起,并且越来越被认为是全球神经系统疾病的主要原因。癫痫是常见的发病形式。包括计算机断层扫描和磁共振成像在内的神经影像学,结合血清诊断技术,使得对该病的认识有所增加。我们报告了2006年和2008年在奥马尔·邦戈·翁丁巴陆军教学医院诊断出的两例NCC病例(其中一例合并感染HIV)。新发癫痫揭示了这两例病例。使用阿苯达唑、抗癫痫药物和皮质类固醇进行药物治疗后实现了完全康复。在热带国家,NCC应被视为癫痫的主要病因。此外,在流行地区的HIV患者中,NCC应纳入神经系统感染的鉴别诊断。

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