Lichtenstein Brian J, Bichell David P, Connolly Dana M, Lamberti John J, Shepard Suzanne M, Seslar Stephen P
University of California, San Diego School of Medicine, La Jolla, CA, USA.
Pediatr Cardiol. 2010 Oct;31(7):1016-24. doi: 10.1007/s00246-010-9754-1. Epub 2010 Aug 6.
Permanent cardiac pacing in pediatric patients presents challenges related to small patient size, complex anatomy, electrophysiologic abnormalities, and limited access to cardiac chambers. Epicardial pacing currently remains the conventional technique for infants and patients with complex congenital heart disease. Pacemaker lead failure is the major source of failure for such epicardial systems. The authors hypothesized that a retrocostal surgical approach would reduce the rate of lead failure due to fracture compared with the more traditional subrectus and subxiphoid approaches. To evaluate this hypothesis, a retrospective chart review analyzed patients with epicardial pacemaker systems implanted or followed at Rady Children's Hospital San Diego between January 1980 and May 2007. The study cohort consisted of 219 patients and a total of 620 leads with epicardial pacemakers. Among these patients, 84% had structural congenital heart disease, and 45% were younger than 3 years at time of the first implantation. The estimated lead survival was 93% at 2 years and 83% at 5 years. The majority of leads failed due to pacing problems (54%), followed by lead fracture (31%) and sensing problems (14%). When lead failure was adjusted for length of follow-up period, no significant differences in the rates of failure by pocket location were found.
小儿患者的永久性心脏起搏面临诸多挑战,这些挑战与患者体型小、解剖结构复杂、电生理异常以及进入心脏腔室的途径有限有关。目前,心外膜起搏仍是婴儿和复杂先天性心脏病患者的传统技术。起搏器导线故障是此类心外膜系统故障的主要原因。作者推测,与更传统的腹直肌下和剑突下途径相比,肋后手术方法将降低因导线断裂导致的导线故障发生率。为了评估这一假设,一项回顾性图表审查分析了1980年1月至2007年5月在圣地亚哥拉迪儿童医院植入或随访的心外膜起搏器系统患者。研究队列包括219名患者和总共620根心外膜起搏器导线。在这些患者中,84%患有结构性先天性心脏病,45%在首次植入时年龄小于3岁。估计导线在2年时的生存率为93%,在5年时为83%。大多数导线故障是由于起搏问题(54%),其次是导线断裂(31%)和感知问题(14%)。当根据随访期长度对导线故障进行调整时,未发现不同部位导线故障率的显著差异。