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基层医疗中亚临床甲状腺功能减退症的实际情况。

The reality of subclinical hypothyroidism in general practice.

作者信息

Gibbons Veronique, Lillis Steven, Conaglen John, Lawrenson Ross

机构信息

Waikato Clinical School, The University of Auckland, Hamilton, New Zealand.

出版信息

J Prim Health Care. 2009 Sep;1(3):215-21.

Abstract

INTRODUCTION

Subclinical hypothyroidism (SCH) is common, reported to affect 4-10% of the adult population. Recommendations for treatment of SCH are contentious, with protagonists even disagreeing over the rationale for medical intervention. How general practitioners (GPs) manage patients with elevated thyroid stimulating hormone (TSH) and normal thyroid hormone results are unknown. This study aimed to explore how GPs think about diagnosing and managing SCH.

METHODS

A qualitative study using focus groups conducted between December 2007 and March 2008 to understand how GPs perceive SCH and their diagnostic and management process.

FINDINGS

Thirteen GPs in three focus groups in Waikato, New Zealand participated. There is wide variability in how GPs perceive SCH and their knowledge of the disease. A patient-centred approach to diagnosis and management was commonly reported. Consideration of overt pathology and medicolegal issues also influenced perceptions of SCH, but lack of evidence regarding outcomes of treatment made such issues complex.

CONCLUSION

SCH remains a complex entity because of ambiguity regarding symptoms, uncertainty regarding prognosis and variation in advice regarding treatment. This complexity is reflected in the disparate responses by GPs to the diagnosis and management of SCH.

摘要

引言

亚临床甲状腺功能减退症(SCH)很常见,据报道影响4%至10%的成年人口。关于SCH治疗的建议存在争议,支持者甚至在医学干预的基本原理上也存在分歧。全科医生(GP)如何管理促甲状腺激素(TSH)升高而甲状腺激素结果正常的患者尚不清楚。本研究旨在探讨全科医生如何看待SCH的诊断和管理。

方法

采用焦点小组进行定性研究,时间为2007年12月至2008年3月,以了解全科医生如何看待SCH及其诊断和管理过程。

结果

新西兰怀卡托地区三个焦点小组的13名全科医生参与了研究。全科医生对SCH的看法及其对该疾病的了解存在很大差异。普遍报告采用以患者为中心的诊断和管理方法。对明显病理和法医学问题的考虑也影响了对SCH的看法,但缺乏治疗结果的证据使这些问题变得复杂。

结论

由于症状不明确、预后不确定以及治疗建议存在差异,SCH仍然是一个复杂的实体。这种复杂性反映在全科医生对SCH诊断和管理的不同反应中。

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