Department of Anesthesiology, Pain and Palliative Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Physiother Theory Pract. 2011 Feb;27(2):117-24. doi: 10.3109/09593981003761509. Epub 2010 Aug 8.
The aim of this pilot study is to determine the feasibility and preliminary effectiveness of an individually designed preoperative therapeutic exercise program (PreTEP), in patients recently diagnosed with cancer and awaiting elective surgery. The purpose is to improve their physical fitness levels during this waiting period with the intention of decreasing postoperative morbidity. A preexperimental pilot study was performed at the University Medical Center Utrecht, The Netherlands. Thirty-nine patients diagnosed with cancer, scheduled for elective abdominal/thoracic surgery, were referred to a multidisciplinary preoperative screening. Fifteen patients (38%) participated in PreTEP. Participants were satisfied and motivated during the period of training (on average 5 weeks) in which they attended 84% of the sessions. Cardiorespiratory fitness (A strand-test) and muscle strength (Handheld Dynamometry) increased significantly, from 25 to 33 mL/kg/min, respectively (p<0.01; 95% confidence interval [CI]=-0.011 to -0.004) and from 894 Newton (N) to 961N (p<0.01; 95% CI=-94.53 to -39.0). No adverse events occurred during the training period. PreTEP was shown to be feasible, safe, and well-tolerated and appreciated by participants. Despite the relatively short period of training, physical fitness improved in all participants.
本初步研究旨在确定为近期诊断患有癌症且等待择期手术的患者设计的个体化术前治疗性运动方案（PreTEP）的可行性和初步效果。目的是在等待期间提高他们的身体健康水平，以期降低术后发病率。在荷兰乌得勒支大学医学中心进行了一项预实验性初步研究。39 名被诊断患有癌症、计划接受腹部/胸部择期手术的患者被转介到多学科术前筛查。15 名患者（38%）参加了 PreTEP。参与者在训练期间（平均 5 周）感到满意和有动力，他们参加了 84%的课程。心肺功能（A 链测试）和肌肉力量（手持式测力计）分别显著增加，从 25 增加到 33 mL/kg/min（p<0.01；95%置信区间 [CI]=-0.011 至 -0.004）和从 894 牛顿（N）增加到 961N（p<0.01；95% CI=-94.53 至 -39.0）。在训练期间没有发生不良事件。PreTEP 被证明是可行的、安全的、耐受良好的，并且受到参与者的赞赏。尽管训练时间相对较短，但所有参与者的身体健康状况都有所改善。
