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在加速康复方案中择期行结直肠手术患者的住院时间预测因素。

Predictors of length of stay in patients having elective colorectal surgery within an enhanced recovery protocol.

机构信息

The Combined Gastroenterology Research Unit, Scarborough Hospital, Woodlands Drive, YO12 6QL Scarborough, United Kingdom.

出版信息

Int J Surg. 2010;8(8):628-32. doi: 10.1016/j.ijsu.2010.07.294. Epub 2010 Aug 4.

Abstract

BACKGROUND

Enhanced recovery after surgery (ERAS) pathways has been shown to minimize the duration of hospital stay. The aim of this study was to identify which factors have the greatest impact at reducing the length of stay within an enhanced recovery programme.

METHODS

A retrospective case note review of patients undergoing open elective colorectal resections between August 2007 and May 2009 was performed. Data on numerous pre, peri and postoperative variables were collected. Postoperative complications, readmissions, length of stay and fitness for discharge were recorded. Using logistic regression analysis, univariate and multivariate analysis of predictors for a shorter hospital stay was performed. Odd ratios and ninety-five percent confidence intervals were calculated and a p-value of less than 0.05 was significant.

RESULTS

There were 231 patients, of which 130 were female. Median age was 68 (IQR 56-76) years. Median length of stay was 6 (IQR 5-9) days. On multivariate analysis, ASA grade (OR 2.85 (95%CI 1.17-6.89), p = 0.040), the avoidance of oral opiates in the postoperative period (OR 0.39 (95%CI 0.18-0.84), p = 0.016) and the duration of use of epidurals for postoperative analgesia (OR 0.44 (95%CI 0.12-0.94), p = 0.023) were found to be significant predictors of reduced hospital stay.

CONCLUSION

Lower ASA grade, use of epidurals and avoidance of regular oral opiates are associated with an earlier discharge in an ERAS programme.

摘要

背景

术后加速康复(ERAS)方案已被证明可最大程度地缩短住院时间。本研究旨在确定在 ERAS 方案中,哪些因素对缩短住院时间的影响最大。

方法

对 2007 年 8 月至 2009 年 5 月期间行择期开腹结直肠切除术的患者进行回顾性病历审查。收集了大量术前、术中和术后变量的数据。记录术后并发症、再入院、住院时间和出院适应情况。使用逻辑回归分析,对缩短住院时间的预测因素进行单变量和多变量分析。计算比值比和 95%置信区间,并将 p 值小于 0.05 视为具有统计学意义。

结果

共纳入 231 例患者,其中 130 例为女性。中位年龄为 68(IQR 56-76)岁。中位住院时间为 6(IQR 5-9)天。多变量分析显示,ASA 分级(OR 2.85(95%CI 1.17-6.89),p = 0.040)、术后避免使用口服阿片类药物(OR 0.39(95%CI 0.18-0.84),p = 0.016)和术后使用硬膜外镇痛的时间(OR 0.44(95%CI 0.12-0.94),p = 0.023)是缩短住院时间的显著预测因素。

结论

ASA 分级较低、使用硬膜外镇痛和避免常规口服阿片类药物与 ERAS 方案中的提前出院相关。

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