幼鼠的吮乳行为：一种发育中的神经递质系统的调节作用。

Suckling behavior of the infant rat: modulation by a developing neurotransmitter system.

作者信息

Nock B, Williams C L, Hall W G

出版信息

Pharmacol Biochem Behav. 1978 Mar;8(3):277-80. doi: 10.1016/0091-3057(78)90316-7.

PMID:206914

Abstract

Drugs which alter serotonin receptor activity modified the suckling behavior of 20-day-old rat pups. Suckling could be reinstated in nondeprived pups, which normally do not suckle, by blockade of serotonin receptors with methysergide. Stimulation of serotonin receptors with quipazine inhibited suckling in deprived pups, and this effect was prevented by methysergide pretreatment. This evidence suggests that suckling in weaning age pups is controlled by a serotonergic inhibitory mechanism.

摘要

改变血清素受体活性的药物会改变20日龄幼鼠的吮乳行为。用美西麦角阻断血清素受体，可使通常不吮乳的未断奶幼鼠恢复吮乳行为。用喹哌嗪刺激血清素受体可抑制断奶幼鼠的吮乳行为，而美西麦角预处理可防止这种效应。这一证据表明，断奶期幼鼠的吮乳行为受血清素能抑制机制的控制。