Gordon B G, Kiwanuka J, Kadushin J
Department of Pediatrics, University of Nebraska Medical Center, Omaha 68198-2185.
Am J Pediatr Hematol Oncol. 1991 Summer;13(2):164-7. doi: 10.1097/00043426-199122000-00011.
We describe a child with Hodgkin's disease (HD) who presented with profound neutropenia, secondary to an antineutrophil antibody. The patient responded to intravenous immunoglobulin (IVIG), with prompt and sustained improvement in total white blood cell count (WBC) and absolute neutrophil count (ANC). The literature pertaining to autoimmune cytopenias complicating HD is reviewed, as well as the role of IVIG in management of these disorders.
我们描述了一名患有霍奇金淋巴瘤（HD）的儿童，该患儿因抗中性粒细胞抗体继发严重中性粒细胞减少。患者对静脉注射免疫球蛋白（IVIG）有反应，总白细胞计数（WBC）和绝对中性粒细胞计数（ANC）迅速且持续改善。本文回顾了有关HD并发自身免疫性血细胞减少的文献，以及IVIG在这些疾病管理中的作用。
