Institute of Molecular Biology, University of Oregon, 1370 Franklin Boulevard, Eugene, OR 97403, USA.
Curr Biol. 2010 Aug 10;20(15):R646-8. doi: 10.1016/j.cub.2010.06.011.
The protein Lethal giant larvae (LGL) regulates cell polarity in diverse animal models. Now, an LGL orthologue has been identified in the worm Caenorhabditis elegans and is shown to function redundantly with a worm-specific polarity protein, PAR-2.
蛋白质致死巨幼虫(Lethal giant larvae,LGL)在多种动物模型中调节细胞极性。现在,已经在线虫秀丽隐杆线虫中鉴定出一个 LGL 同源物,并显示其与一种特定于线虫的极性蛋白 PAR-2 具有冗余功能。