Department of Dermatology, University of Muenster, Muenster, Germany.
Lupus. 2010 Aug;19(9):1144-52. doi: 10.1177/0961203310370346.
Epidemiological data and standard European guidelines for the diagnosis and treatment of cutaneous lupus erythematosus (CLE) are lacking in the current literature. In order to provide a standardized tool for an extensive consistent data collection, a study group of the European Society of Cutaneous Lupus Erythematosus (EUSCLE) recently developed a Core Set Questionnaire for the assessment of patients with different subtypes of CLE. The EUSCLE Core Set Questionnaire includes six sections on patient data, diagnosis, skin involvement, activity and damage of disease, laboratory analysis, and treatment. An instrument like the EUSCLE Core Set Questionnaire is essential to gain a broad and comparable data collection of patients with CLE from different European centres and to achieve consensus concerning clinical standards for the disease. The data will also be important for further characterization of the different CLE subtypes and the evaluation of therapeutic strategies; moreover, the EUSCLE Core Set Questionnaire might also be useful for the comparison of data in clinical trials. In this review, the impact of the EUSCLE Core Set Questionnaire is discussed in detail with regard to clinical and serological features as well as therapeutic modalities in CLE.
目前的文献中缺乏有关皮肤红斑狼疮（CLE）的流行病学数据和欧洲标准指南。为了提供一种广泛一致的数据收集的标准化工具，欧洲皮肤狼疮红斑狼疮学会（EUSCLE）的一个研究小组最近开发了一种核心问卷，用于评估不同亚型 CLE 患者。EUSCLE 核心问卷包括六个部分：患者数据、诊断、皮肤受累、疾病活动和损害、实验室分析和治疗。像 EUSCLE 核心问卷这样的工具对于从不同欧洲中心广泛收集 CLE 患者的可比数据以及就疾病的临床标准达成共识至关重要。这些数据对于进一步确定不同 CLE 亚型以及评估治疗策略也很重要；此外，EUSCLE 核心问卷也可能对临床试验数据的比较有用。在这篇综述中，详细讨论了 EUSCLE 核心问卷对 CLE 的临床和血清学特征以及治疗方式的影响。
