Erasmus University Medical Center, Department of Ophthalmology, 3000-CA Rotterdam, The Netherlands.
Br J Ophthalmol. 2011 Aug;95(8):1082-5. doi: 10.1136/bjo.2010.183566. Epub 2010 Aug 6.
To determine the amount of myopic shift in children after cataract surgery with intraocular lens (IOL) implantation and to evaluate success in achieving the target refraction.
The children were assigned into three groups depending on age at time of surgery: Group A, 0-1 years old; Group B, 1-7 years old; Group C, 7-18 years old. Multiple regression analysis was used to create a formula for expected myopic shift and to find out which variables were associated with a higher absolute prediction error.
Children less than 12 months of age experienced higher myopic shifts and a larger mean rate of refractive change per year compared with older children. We found higher myopic shifts in younger children at time of surgery and children with unilateral cataract. Absolute prediction error was significantly higher in Group A compared with Groups B and C (p=0.022 and p=0.037, respectively). Multiple regression analysis showed that corneal radius was the only variable significantly associated with absolute prediction error.
Our data demonstrate the complexity in predicting the postoperative refraction in children under 1 year old and show that age at surgery and laterality are factors to consider when deciding which IOL power to implant in children.
确定儿童白内障手术后眼内晶状体（IOL）植入术后的近视漂移量，并评估达到目标屈光度的成功率。
根据手术时的年龄将儿童分为三组：A 组，0-1 岁；B 组，1-7 岁；C 组，7-18 岁。采用多元回归分析创建预期近视漂移的公式，并找出与更高绝对预测误差相关的变量。
与年龄较大的儿童相比，12 个月以下的儿童经历了更高的近视漂移和更大的每年平均屈光变化率。我们发现手术时年龄较小的儿童和单侧白内障的儿童有更高的近视漂移。与 B 组和 C 组相比，A 组的绝对预测误差明显更高（p=0.022 和 p=0.037）。多元回归分析表明，角膜半径是与绝对预测误差显著相关的唯一变量。
我们的数据表明，1 岁以下儿童术后屈光度的预测非常复杂，并表明手术时的年龄和偏侧性是决定儿童植入哪种 IOL 时需要考虑的因素。
