Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, 32, Gisborne Street, East Melbourne, Victoria 3002, Australia.
Br J Ophthalmol. 2011 Aug;95(8):1044-50. doi: 10.1136/bjo.2010.185868. Epub 2010 Aug 7.
Keratoconus is an ectatic corneal dystrophy and is a leading indication for corneal transplantation surgery worldwide. The disease was first described in detail more than 150 years ago by Dr John Nottingham, but the understanding of the disease and its management have undergone significant changes over the last few decades. Corneal specialists have adopted new techniques and technologies for the effective management of keratoconus, while adhering to the age-old concepts of contact lens fitting and penetrating keratoplasty. Lamellar keratoplasty has been revived with improved outcomes and devices such as intracorneal ring segments are being used to treat cases of early keratoconus effectively. This review article discusses the current scenario on the surgical as well as non-surgical management of keratoconus with a focus on the established, novel and emerging treatment modalities.
圆锥角膜是一种扩张性角膜病变,是全球角膜移植手术的主要指征。该疾病在 150 多年前由 John Nottingham 医生首次详细描述,但近年来对该疾病的认识及其管理已发生重大变化。角膜专家为圆锥角膜的有效管理采用了新技术和新设备,同时坚持接触镜适配和穿透性角膜移植的古老理念。板层角膜移植术已恢复应用,且取得了更好的效果,诸如角膜内环段等器械也被用于有效治疗早期圆锥角膜。本文讨论了圆锥角膜的手术和非手术治疗现状,重点介绍了已确立、新颖和新兴的治疗方法。