Netherlands Institute for Innovative Ocular Surgery (NIIOS), Rotterdam, The Netherlands.
University of Alberta, Canada.
Curr Opin Ophthalmol. 2019 Jul;30(4):249-255. doi: 10.1097/ICU.0000000000000570.
Bowman layer transplantation is a novel technique that may stabilize progressive ectatic corneal changes in eyes with keratoconus, which are too steep or too thin for ultraviolet corneal crosslinking or intracorneal ring segments. In this way, patients can maintain stable vision with contact lenses, and avoid or postpone more invasive corneal transplants, such as penetrating keratoplasty or deep anterior lamellar keratoplasty. This review aims to summarize the currently available literature on Bowman layer transplantation.
Bowman layer transplantation seems to be a promising, minimally invasive procedure for managing advanced keratoconus with a reported 5-year success rate of 84%. The procedure allows patients to maintain acceptable visual acuity with glasses or contact lens correction. Although graft preparation and surgical technique can be challenging, adaptation of technologies, such as femtosecond laser and intraoperative anterior segment optical coherence tomography, may help overcome these barriers to enable Bowman layer transplantation to become a more widely adopted procedure.
Bowman layer transplantation may offer an alternative, less invasive treatment option for eyes with advanced, progressive keratoconus.
Bowman 层移植是一种新的技术，可能稳定圆锥角膜患者进行性扩张性角膜变化，这些患者的角膜对于紫外线角膜交联或角膜内环段术而言过于陡峭或过薄。通过这种方式，患者可以通过接触镜维持稳定的视力，并避免或推迟更具侵袭性的角膜移植，如穿透性角膜移植或深板层角膜移植。本综述旨在总结目前关于 Bowman 层移植的文献。
Bowman 层移植似乎是一种有前途的、微创的治疗晚期圆锥角膜的方法，报告的 5 年成功率为 84%。该手术使患者能够通过眼镜或隐形眼镜矫正获得可接受的视力。尽管移植物的制备和手术技术具有挑战性，但飞秒激光和术中眼前节光学相干断层扫描等技术的应用可能有助于克服这些障碍，使 Bowman 层移植成为一种更广泛采用的手术方法。
Bowman 层移植可能为进展性、进行性圆锥角膜的患者提供一种替代的、微创的治疗选择。
