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["3 + 6"方案在肺结核常规治疗中的近期及远期疗效]

[Immediate and late results of the use of "3 + 6" regimens in the routine treatment of pulmonary tuberculosis].

作者信息

Didilescu C, Panghea P, Pavlidi N, Purcăreanu G, Roman G

出版信息

Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Pneumoftiziol. 1978 Jan-Mar;27(1):37-40.

PMID:206942
Abstract

An assessment is carried out of the results obtained in the Constantza County after over 2 years of application of the "3 + 6" regimens (INH + RMP and INH + SM + EMB) in a group of 119 patients with initially bacteriologically confirmed pulmonary tuberculosis. The standard regimens applied were not replaced with other regimens. The dynamics of negativation in cultures confirmed that over 50% of the patients had become negative after the first month of treatment. For practical purposes negativation was completed before 3 months in all the cases. The only two failures were recorded in the first three months after the treatment was ended. No re-positivation was noted in the second year of the follow-up. A stable resolution was achieved in 98% of the patients.

摘要

对康斯坦察县119例初治痰菌阳性肺结核患者应用“3 + 6”方案(异烟肼+利福平及异烟肼+链霉素+乙胺丁醇)2年多后的治疗结果进行了评估。所应用的标准方案未被其他方案取代。培养转阴动态显示,超过50%的患者在治疗第1个月后转阴。实际上,所有病例均在3个月内完成转阴。仅在治疗结束后的前3个月记录到2例治疗失败。随访第二年未发现复阳。98%的患者病情得到稳定缓解。

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