Bukowski J A, Goldstein M D, Johnson B B
Division of Science and Research, New Jersey Department of Environmental Protection, Trenton.
Arch Environ Health. 1991 Jul-Aug;46(4):230-6. doi: 10.1080/00039896.1991.9937454.
An estimated two million tons of chromate production waste pollution has caused a major environmental and public health concern in Hudson County, New Jersey. As part of an occupational exposure assessment, urinary and red blood cell (RBC) chromium measurements were performed on 52 state employees who worked either near a contaminated site or elsewhere. Samples were collected so as to minimize contamination, and they were analyzed using sensitive techniques. These workers also completed a questionnaire that addressed potentially important third variables. Individual analyses suggested that exercise, drinking beer, past employment in chromium-related occupations, and diabetic status had an important effect on urinary chromium levels. These variables were entered into a regression model and were all found to be significant predictors of urinary chromium level (p less than .10). Some variables were also examined for their influence on RBC chromium level, but none had a measurable effect.
据估计，200万吨铬酸盐生产废物污染已在新泽西州哈德逊县引发了重大的环境和公共卫生问题。作为职业暴露评估的一部分，对52名在受污染场地附近工作或在其他地方工作的州政府雇员进行了尿液和红细胞（RBC）铬含量测量。采集样本时尽量减少污染，并使用灵敏技术进行分析。这些工人还填写了一份涉及潜在重要第三变量的问卷。个体分析表明，运动、喝啤酒、过去从事与铬相关职业以及糖尿病状况对尿铬水平有重要影响。将这些变量纳入回归模型，发现它们都是尿铬水平的显著预测因子（p小于0.10）。还研究了一些变量对红细胞铬水平的影响，但没有一个有可测量的效果。
