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新泽西州铬废物场地附近的社区暴露与医学筛查

Community exposure and medical screening near chromium waste sites in New Jersey.

作者信息

Fagliano J A, Savrin J, Udasin I, Gochfeld M

机构信息

Consumer and Environmental Health Services, New Jersey Department of Health and Senior Services, Trenton, New Jersey 08625, USA.

出版信息

Regul Toxicol Pharmacol. 1997 Aug;26(1 Pt 2):S13-22. doi: 10.1006/rtph.1997.1134.

Abstract

Chromium waste slag containing potentially hazardous levels of hexavalent chromium was used as fill material at more than 160 residential, industrial, and recreational sites. Persons living or working in the vicinity of the sites may have been exposed through inhalation, ingestion, or skin contact with contaminated soils and dusts. In 1992-1993, the New Jersey Department of Health and Senior Services (NJDHSS) and the Environmental and Occupational Health Sciences Institute (EOHSI) conducted a screening project to assess exposure to chromium and to provide medical evaluations to people living in 14 residential areas or working in 78 workplaces near chromium waste sites. The screening included a physical examination for irritant or allergic effects and a urine chromium test for recent exposure. Participants were referred for follow-up medical evaluation if specific criteria were met. Of 800 residents and 938 workers receiving the screening physical examination, 32 adults were referred for follow-up evaluation. Of 806 residents and 934 workers submitting a urine specimen for chromium analysis, 158 adults and children had levels exceeding specified criteria and were referred for follow-up evaluation. The proportion of persons referred on the basis of the urine chromium test varied among screened groups. Multiple linear regression models showed that average urine chromium differences between residents and a comparison group, adjusting for potential confounders, were highest in children under 6 years of age. Most of the persons undergoing the follow-up medical examinations revealed no apparent clinical effects attributable to chromium exposure. The screening results indicated the need for expanded environmental evaluation in specific residential areas and workplaces.

摘要

含有潜在危险水平六价铬的铬渣被用作160多个住宅、工业和娱乐场所的填充材料。在这些场所附近生活或工作的人可能通过吸入、摄入或皮肤接触受污染的土壤和灰尘而接触到铬。1992年至1993年,新泽西州卫生与高级服务部(NJDHSS)以及环境与职业健康科学研究所(EOHSI)开展了一项筛查项目,以评估铬暴露情况,并为居住在14个居民区或在铬废物场地附近78个工作场所工作的人员提供医学评估。筛查包括针对刺激或过敏效应的体格检查以及针对近期暴露情况的尿铬检测。如果符合特定标准,参与者将被转介进行后续医学评估。在接受筛查体格检查的800名居民和938名工人中,有32名成年人被转介进行后续评估。在提交尿样进行铬分析的806名居民和934名工人中,有158名成年人和儿童的铬水平超过了指定标准,并被转介进行后续评估。根据尿铬检测结果被转介的人员比例在各筛查组中有所不同。多元线性回归模型显示,在调整潜在混杂因素后,居民与对照组之间的平均尿铬差异在6岁以下儿童中最高。大多数接受后续医学检查的人未显示出因铬暴露而产生的明显临床效应。筛查结果表明需要在特定居民区和工作场所开展更广泛的环境评估。

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