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完全内镜下侧甲状旁腺切除术:200 例患者的前瞻性评估。ESES 2010 年维也纳会议发言。

Totally endoscopic lateral parathyroidectomy: prospective evaluation of 200 patients. ESES 2010 Vienna presentation.

机构信息

Department of Digestive, Hepatobiliary, and Endocrine Surgery, CHU Nancy-Brabois (Hopital Adultes), University of Nancy, 11 allée du morvan, 54511 Vandoeuvre-les-Nancy, France.

出版信息

Langenbecks Arch Surg. 2010 Sep;395(7):935-40. doi: 10.1007/s00423-010-0687-1. Epub 2010 Aug 6.

DOI:10.1007/s00423-010-0687-1
PMID:20694475
Abstract

PURPOSE

Several new minimally invasive techniques (mini-open, video-assisted, and endoscopic procedures) for parathyroidectomy have been described. However, totally endoscopic lateral approach parathyroidectomy (Henry technique) is not routinely performed.

METHODS

This is a prospective study of 200 consecutive patients that underwent totally endoscopic lateral parathyroidectomy.

RESULTS

Two hundred of 387 patients (52%) with primary hyperparathyroidism were included. Fifty-six patients (28%) were converted to open parathyroidectomy. Causes for conversion were lack of intraoperative localization (11%), difficult dissection (10%), bleeding (4%), failure of normalization of IOPTH results (2%), and other causes (1%). Gland localization (areas 1 to 2 versus area 3) and CaPTHus score (<3 versus ≥3) were not associated with the risk of conversion. Mean postoperative follow-up was 13 months, and 196 patients (98%) were cured.

CONCLUSIONS

Totally endoscopic lateral approach can be proposed in more than half of the patients with good immediate results. Conversion rate remains important and may explain low acceptance rate of this technique.

摘要

目的

已经描述了几种新的微创技术(微创、视频辅助和内窥镜手术)用于甲状旁腺切除术。然而,完全内窥镜侧入路甲状旁腺切除术(Henry 技术)并未常规进行。

方法

这是一项对 200 例连续接受完全内窥镜侧甲状旁腺切除术的患者进行的前瞻性研究。

结果

387 例原发性甲状旁腺功能亢进症患者中,有 200 例(52%)被纳入研究。56 例(28%)患者转为开放性甲状旁腺切除术。转为开放性手术的原因包括术中定位缺失(11%)、难以分离(10%)、出血(4%)、IOPTH 结果未正常化(2%)和其他原因(1%)。腺体定位(1 区至 2 区与 3 区)和 CaPTHus 评分(<3 与≥3)与转换风险无关。平均术后随访 13 个月,196 例(98%)患者治愈。

结论

对于大多数患者来说,完全内窥镜侧入路可获得良好的即刻效果。转换率仍然很重要,这可能解释了该技术低接受率的原因。

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Weight difference between double parathyroid adenomas is the cause of false-positive IOPTH test after resection of the first lesion.双甲状旁腺腺瘤之间的重量差异是切除第一个病变后假性阳性 IOPTH 试验的原因。
World J Surg. 2010 Jun;34(6):1337-42. doi: 10.1007/s00268-010-0413-8.
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Randomized clinical trial comparing open with video-assisted minimally invasive parathyroid surgery for primary hyperparathyroidism.随机临床试验比较原发性甲状旁腺功能亢进的开放手术与电视辅助微创甲状旁腺手术。
Br J Surg. 2010 Feb;97(2):177-84. doi: 10.1002/bjs.6810.
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The value of intraoperative parathyroid hormone monitoring in localized primary hyperparathyroidism: a cost analysis.
Main Surgical Principles and Methods in Surgical Treatment of Primary Hyperparathyroidism.
原发性甲状旁腺功能亢进症外科治疗的主要手术原则及方法
Sisli Etfal Hastan Tip Bul. 2019 Dec 3;53(4):337-352. doi: 10.14744/SEMB.2019.67944. eCollection 2019.
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Surgical options in treating patients with primary hyperparathyroidism.治疗原发性甲状旁腺功能亢进症患者的手术选择。
Radiol Oncol. 2020 Feb 29;54(1):22-32. doi: 10.2478/raon-2020-0010.
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Systematic review of cure and recurrence rates following minimally invasive parathyroidectomy.微创甲状旁腺切除术后治愈率和复发率的系统评价
BJS Open. 2018 May 28;2(6):364-370. doi: 10.1002/bjs5.77. eCollection 2018 Dec.
6
Transoral endoscopic parathyroidectomy vestibular approach: a novel scarless parathyroid surgery.经口内镜下甲状旁腺切除术前庭入路:一种新型的无疤痕甲状旁腺手术。
Surg Endosc. 2017 Sep;31(9):3755-3763. doi: 10.1007/s00464-016-5397-5. Epub 2016 Dec 28.
7
Endoscopic and robotic parathyroidectomy in patients with primary hyperparathyroidism.原发性甲状旁腺功能亢进患者的内镜及机器人甲状旁腺切除术
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Surgical strategy for sporadic primary hyperparathyroidism an evidence-based approach to surgical strategy, patient selection, surgical access, and reoperations.散发性原发性甲状旁腺功能亢进症的手术策略:手术策略、患者选择、手术入路及再次手术的循证方法
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Is minimally invasive parathyroidectomy without QPTH monitoring justified?不进行快速甲状旁腺激素(QPTH)监测的微创甲状旁腺切除术是否合理?
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Do patients undergoing parathyroidectomy for primary hyperparathyroidism in San Francisco, CA, and Bursa, Turkey, differ?在加利福尼亚州旧金山和土耳其布尔萨接受原发性甲状旁腺功能亢进甲状旁腺切除术的患者有差异吗?
Am J Surg. 2009 Aug;198(2):188-92. doi: 10.1016/j.amjsurg.2008.09.031. Epub 2009 Mar 23.
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