[Kinetics of cellular elements in the neointima of synthetic prostheses implanted into the rabbit aorta during development of experimental atherosclerosis].

Experimental atherosclerosis in 30 rabbits was combined with the implantation into the abdominal aorta of the synthetic prosthesis MPL-79. Formation of neointima and transformation of mesenchymal cells into the endothelial ones are studied using scanning and translucent electron microscopy and autoradiography. Neointimal hyperplasia is shown to result in significant narrowing of the prosthesis lumen up to its complete occlusion. It is important that neointima fibroplasia is particularly intense against the background of progressing atherosclerosis.