Mori Y, Kuroki Y, Yamamoto R, Fujimoto A, Okumo H, Kubo M
Department of Orthopaedic Surgery, Showa University Fujigaoka Hospital, Yokohama, Japan.
Arthroscopy. 1991;7(2):182-97. doi: 10.1016/0749-8063(91)90107-9.
An arthroscopic and histological investigation of patellar chondropathy in adolescents was performed in 98 knees of 83 patients who were classified into three clinical types of patellofemoral disorder. These were the anterior knee pain syndrome, idiopathic chondropathy, and unstable patella. Histological findings suggested little evidence of progression to high-grade chondropathy in the patients with anterior knee pain syndrome, and this may account for the resolution of clinical symptoms in this group. Even in patients with high-grade lesions in the idiopathic chondropathy and unstable patella groups, histological observations indicated that these lesions could heal either by intrinsic (fibrous metaplasia of chondrocytes and regeneration of matrix) or extrinsic repair. Chondropathy in adolescents may be similar to the early changes of osteoarthritis of the knee. However, chondropathy shows far more potential for repair by the synovium and/or the cartilage itself than does osteoarthritis.
对83例患者的98个膝关节进行了关节镜检查和组织学研究，这些患者被分为三种临床类型的髌股关节紊乱，即膝前疼痛综合征、特发性软骨病和髌骨不稳定。组织学结果表明，膝前疼痛综合征患者进展为高级别软骨病的证据很少，这可能是该组临床症状缓解的原因。即使在特发性软骨病和髌骨不稳定组中存在高级别病变的患者，组织学观察也表明这些病变可以通过内在修复（软骨细胞的纤维化生和基质再生）或外在修复愈合。青少年软骨病可能类似于膝关节骨关节炎的早期变化。然而，与骨关节炎相比，软骨病通过滑膜和/或软骨自身修复的潜力要大得多。
