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The renin, angiotensin, aldosterone, and obesity connection.

作者信息

Luft Friedrich

机构信息

Charité Medical Faculty, Experimental and Clinical Research Center, Berlin, Germany.

出版信息

J Mol Med (Berl). 2010 Sep;88(9):861-4. doi: 10.1007/s00109-010-0664-8.

DOI:10.1007/s00109-010-0664-8

PMID:20697685

Abstract

摘要

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Direct renin inhibition improved insulin resistance and adipose tissue dysfunction in type 2 diabetic KK-A(y) mice.

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Adipokines and cardiometabolic profile in primary hyperaldosteronism.

J Clin Endocrinol Metab. 2010 May;95(5):2391-8. doi: 10.1210/jc.2009-2204. Epub 2010 Mar 1.

Mineralocorticoid receptors, salt-sensitive hypertension, and metabolic syndrome.

Hypertension. 2010 Apr;55(4):813-8. doi: 10.1161/HYPERTENSIONAHA.109.149062. Epub 2010 Feb 22.

Metabolic effects of low dose angiotensin converting enzyme inhibitor in dietary obesity in the rat.

Nutr Metab Cardiovasc Dis. 2010 Jan;20(1):49-55. doi: 10.1016/j.numecd.2009.02.004. Epub 2009 Apr 9.

Energy metabolism in human renin-gene transgenic rats: does renin contribute to obesity?

Hypertension. 2009 Mar;53(3):516-23. doi: 10.1161/HYPERTENSIONAHA.108.124966. Epub 2009 Jan 26.

Mice lacking angiotensin-converting enzyme have increased energy expenditure, with reduced fat mass and improved glucose clearance.

Proc Natl Acad Sci U S A. 2008 May 6;105(18):6531-6. doi: 10.1073/pnas.0802690105. Epub 2008 Apr 28.

Increased energy expenditure, dietary fat wasting, and resistance to diet-induced obesity in mice lacking renin.

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Obesity-associated hypertension: new insights into mechanisms.

Hypertension. 2005 Jan;45(1):9-14. doi: 10.1161/01.HYP.0000151325.83008.b4. Epub 2004 Dec 6.

Late-onset obesity in mice transgenic for the human renin gene.

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相似文献

The renin, angiotensin, aldosterone, and obesity connection.

J Mol Med (Berl). 2010 Sep;88(9):861-4. doi: 10.1007/s00109-010-0664-8.

Renin-angiotensin-aldosterone: An inclusive, an invigorative, an interactive and an interminable system.

Pharmacol Res. 2017 Nov;125(Pt A):1-3. doi: 10.1016/j.phrs.2017.07.003. Epub 2017 Jul 12.

The renin-angiotensin system in the year 2000.

J Hum Hypertens. 2000 Oct-Nov;14(10-11):649-66. doi: 10.1038/sj.jhh.1001056.

Renin-angiotensin-aldosterone and hypertension.

Endocr Rev. 1980 Winter;1(1):78-99. doi: 10.1210/edrv-1-1-78.

Biomarkers of activation of renin-angiotensin-aldosterone system in heart failure: how useful, how feasible?

Clin Chim Acta. 2015 Mar 30;443:85-93. doi: 10.1016/j.cca.2014.10.031. Epub 2014 Oct 25.

Roles of the circulating renin-angiotensin-aldosterone system in human pregnancy.

Am J Physiol Regul Integr Comp Physiol. 2014 Jan 15;306(2):R91-101. doi: 10.1152/ajpregu.00034.2013. Epub 2013 Oct 2.

Renin-Angiotensin-Aldosterone Profiles in Pregnant Women With Chronic Hypertension.

Hypertension. 2018 Aug;72(2):417-424. doi: 10.1161/HYPERTENSIONAHA.118.10854. Epub 2018 Jun 25.

A role for the adrenal renin-angiotensin system in the regulation of potassium-stimulated aldosterone production.

Endocrinology. 1985 Nov;117(5):1772-8. doi: 10.1210/endo-117-5-1772.

Hypovolaemia-induced metabolic dysfunction, mediated in part by aldosterone and angiotensin.

J Hypertens. 2009 Oct;27(10):2116; author reply 2116-7. doi: 10.1097/HJH.0b013e32832dd5a2.

Chronobiology of the renin-angiotensin-aldosterone system in dogs: relation to blood pressure and renal physiology.

Chronobiol Int. 2013 Nov;30(9):1144-59. doi: 10.3109/07420528.2013.807275. Epub 2013 Aug 9.

引用本文的文献

Renin-angiotensin system activity in vitamin D deficient, obese individuals with hypertension: An urban Indian study.

Indian J Endocrinol Metab. 2011 Oct;15 Suppl 4(Suppl4):S395-401. doi: 10.4103/2230-8210.86985.

The influence of body mass index and renin-angiotensin-aldosterone system activity on the relationship between 25-hydroxyvitamin D and adiponectin in Caucasian men.

Eur J Endocrinol. 2011 Jun;164(6):995-1002. doi: 10.1530/EJE-11-0025. Epub 2011 Mar 14.

本文引用的文献

Leptin regulates ACE activity in mice.

J Mol Med (Berl). 2010 Sep;88(9):899-907. doi: 10.1007/s00109-010-0649-7. Epub 2010 Jul 8.

Direct renin inhibition improved insulin resistance and adipose tissue dysfunction in type 2 diabetic KK-A(y) mice.

J Hypertens. 2010 Jul;28(7):1471-81. doi: 10.1097/HJH.0b013e32833bc420.

Adipokines and cardiometabolic profile in primary hyperaldosteronism.

J Clin Endocrinol Metab. 2010 May;95(5):2391-8. doi: 10.1210/jc.2009-2204. Epub 2010 Mar 1.

Mineralocorticoid receptors, salt-sensitive hypertension, and metabolic syndrome.

Hypertension. 2010 Apr;55(4):813-8. doi: 10.1161/HYPERTENSIONAHA.109.149062. Epub 2010 Feb 22.

Metabolic effects of low dose angiotensin converting enzyme inhibitor in dietary obesity in the rat.

Nutr Metab Cardiovasc Dis. 2010 Jan;20(1):49-55. doi: 10.1016/j.numecd.2009.02.004. Epub 2009 Apr 9.

Energy metabolism in human renin-gene transgenic rats: does renin contribute to obesity?

Hypertension. 2009 Mar;53(3):516-23. doi: 10.1161/HYPERTENSIONAHA.108.124966. Epub 2009 Jan 26.

Mice lacking angiotensin-converting enzyme have increased energy expenditure, with reduced fat mass and improved glucose clearance.

Proc Natl Acad Sci U S A. 2008 May 6;105(18):6531-6. doi: 10.1073/pnas.0802690105. Epub 2008 Apr 28.

Increased energy expenditure, dietary fat wasting, and resistance to diet-induced obesity in mice lacking renin.

Cell Metab. 2007 Dec;6(6):506-12. doi: 10.1016/j.cmet.2007.10.011.

Obesity-associated hypertension: new insights into mechanisms.

Hypertension. 2005 Jan;45(1):9-14. doi: 10.1161/01.HYP.0000151325.83008.b4. Epub 2004 Dec 6.

Late-onset obesity in mice transgenic for the human renin gene.

Int J Mol Med. 2003 Jun;11(6):723-7.