Skopljanac-Macina Lada, Mahovlić Vesna, Ovanin-Rakić Ana, Barisić Ana, Rajhvajn Sanda, Juric Danijela, Babić Damir, Corusić Ante, Oresković Slavko
Department of Gynecologic Cytology, Zagreb University Hospital Center, Zagreb, Croatia.
Coll Antropol. 2010 Jun;34(2):613-7.
Croatia still has opportunistic screening and the organized national screening has been planned. The European Cervical Cancer Prevention Week was held twice in Croatia, in January 2008 and 2009. Within the first one in 2008, information campaign "For All Women" via mass media was held, and women were invited to the organized free gynecological examination and Papanicolaou test (Pap test) in the University Department of Gynecology and Obstetrics, Zagreb University Hospital Center. Following invitation 481 women attended the testing; the median age was 55 years. There were more women aged > or = 50 (n = 353), with the highest participation in the age group 55-59 years (n = 94). Some women came because of subjective symptoms (n = 10), but the majority of them came only for testing (n = 471). According to history of previous cytological testing, 400 women have had > or = 1 negative findings, 71 women have had > or = 1 positive findings, 9 women attended Pap test for the first time, and 1 woman does not know about previous testing. Cervical cytology was abnormal in 35 women (7.28%), the median age was 42 years with the highest proportion in the age group 30-34 years (n = 7); among all of them 21 women (60%) had no abnormal Pap test previously. The findings were: Atypical squamous cells of undetermined significance--ASC-US (n = 9), ASC cannot exclude high-grade squamous intraepithelial lesion--ASC-H (n = 1), cervical intraepithelial neoplasia--CIN 1 (n = 13), CIN 2 (n = 1), CIN 3 (n = 6), carcinoma planocellulare (n = 2), atypical glandular cells--AGC-favor reactive endocervical cells (n = 3). Among women aged < or = 49 there were 20.47% abnormal findings and among those aged > or = 50, 2.55%. According to 21 positive Pap tests previously, among women aged < or = 49 there were 30.71% while among those aged > or = 50 there were 9.07%. Within the European Cervical Cancer Prevention Week in 2009, employed women from one national company were invited by internal information to the same procedure. A smaller group of younger asymptomatic women came for testing (n = 53), median age 39 years. According to history of previous cytological testing, 50 women have had > or = 1 negative findings, 3 women have had > or = 1 positive findings. In this study, Pap test was positive in 3.77% (n = 2). National screening programme should be focused on the participation of all personally invited women, especially younger age groups and under-screened women. Well designed information campaign should be implemented in national screening programme.
克罗地亚仍在进行机会性筛查，并且已经规划了有组织的全国性筛查。欧洲宫颈癌预防周于2008年1月和2009年在克罗地亚举办了两次。在2008年的第一次活动中，通过大众媒体开展了“关爱所有女性”的宣传活动，并邀请女性前往萨格勒布大学医院中心妇产科大学部参加免费的妇科检查和巴氏试验（Pap试验）。收到邀请后，481名女性参加了检查；中位年龄为55岁。年龄≥50岁的女性更多（n = 353），其中55 - 59岁年龄组的参与率最高（n = 94）。一些女性是因为主观症状前来（n = 10），但她们中的大多数只是为了检查而来（n = 471）。根据既往细胞学检查史，400名女性有≥1次阴性结果，71名女性有≥1次阳性结果，9名女性首次参加Pap试验，1名女性不清楚既往检查情况。35名女性的宫颈细胞学检查结果异常（7.28%），中位年龄为42岁，其中30 - 34岁年龄组比例最高（n = 7）；在所有这些女性中，21名女性（60%）既往Pap试验无异常。检查结果为：意义不明确的非典型鳞状细胞——ASC-US（n = 9），不能排除高级别鳞状上皮内病变的非典型鳞状细胞——ASC-H（n = 1），宫颈上皮内瘤变——CIN 1（n = 13），CIN 2（n = 1），CIN 3（n = 6），扁平细胞癌（n = 2），非典型腺细胞——AGC-倾向反应性宫颈内膜细胞（n = 3）。年龄≤49岁的女性中异常结果占20.47%，年龄≥50岁的女性中占2.55%。根据之前21次阳性的Pap试验结果，年龄≤49岁的女性中占30.71%，年龄≥50岁的女性中占约9.07%。在2009年的欧洲宫颈癌预防周期间，一家全国性公司的在职女性通过内部宣传被邀请参加同样的检查。一小群较年轻无症状的女性前来检查（n = 53），中位年龄39岁。根据既往细胞学检查史，50名女性有≥1次阴性结果，3名女性有≥1次阳性结果。在本研究中，Pap试验阳性率为3.77%（n = 2）。全国性筛查计划应注重所有被个人邀请的女性的参与，尤其是较年轻年龄组和筛查不足的女性。应在全国性筛查计划中实施精心设计的宣传活动。
