足月孕妇在自然发动分娩后发生脐带炎和组织学绒毛膜羊膜炎的频率及危险因素。
The frequency and risk factors of funisitis and histologic chorioamnionitis in pregnant women at term who delivered after the spontaneous onset of labor.
作者信息
Mi Lee Seung, Romero Roberto, Lee Kyung A, Jin Yang Hye, Joon Oh Kyung, Park Chan-Wook, Yoon Bo Hyun
机构信息
Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.
出版信息
J Matern Fetal Neonatal Med. 2011 Jan;24(1):37-42. doi: 10.3109/14767058.2010.482622. Epub 2010 Aug 10.
OBJECTIVE
To examine the frequency and risk factors of funisitis and histologic chorioamnionitis in the placentas of term pregnant women who delivered after the spontaneous onset of labor.
METHODS
The frequency of funisitis and histologic chorioamnionitis was examined in consecutive pregnant women at term with singleton pregnancies who delivered after the spontaneous onset of labor. Nonparametric statistics were used for data analysis.
RESULTS
(1) The frequency of funisitis and histologic chorioamnionitis was 6.7% (88/1316) and 23.6% (310/1316), respectively; (2) Patients with funisitis had significantly higher rates of nulliparity, regional analgesia, operative vaginal delivery, longer duration of labor and rupture of membranes (ROM), and higher gestational age and birthweight than those without funisitis (p < 0.05 for each); (3) Patients with histologic chorioamnionitis had significantly higher rates of nulliparity, oxytocin augmentation, regional analgesia, cesarean section or operative vaginal delivery, longer duration of labor and ROM, and higher gestational age and birthweight than those without histologic chorioamnionitis (p < 0.05 for each); (4) Multiple logistic regression analysis indicated that the longer the duration of labor, the higher the risk of funisitis, and that nulliparity and the duration of labor significantly increased the odds of histologic chorioamnionitis (p < 0.05 for each).
CONCLUSION
The longer the duration of labor, the higher the risk of funisitis and histologic chorioamnionitis in pregnant women at term who delivered after the spontaneous onset of labor.
目的
研究自然发动分娩的足月孕妇胎盘脐带炎和组织学绒毛膜羊膜炎的发生率及危险因素。
方法
对自然发动分娩的足月单胎妊娠孕妇连续进行研究，检查脐带炎和组织学绒毛膜羊膜炎的发生率。采用非参数统计方法进行数据分析。
结果
（1）脐带炎和组织学绒毛膜羊膜炎的发生率分别为6.7%（88/1316）和23.6%（310/1316）；（2）与无脐带炎的患者相比，脐带炎患者的初产、区域镇痛、阴道助产、产程和胎膜破裂时间更长，孕周和出生体重更高（每项p<0.05）；（3）与无组织学绒毛膜羊膜炎的患者相比，组织学绒毛膜羊膜炎患者的初产、缩宫素引产、区域镇痛、剖宫产或阴道助产、产程和胎膜破裂时间更长，孕周和出生体重更高（每项p<0.05）；（4）多因素logistic回归分析表明，产程越长，发生脐带炎的风险越高，初产和产程显著增加组织学绒毛膜羊膜炎的发生几率（每项p<0.05）。
结论
自然发动分娩的足月孕妇，产程越长，发生脐带炎和组织学绒毛膜羊膜炎的风险越高。
Zotero 插件