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[维生素C缺乏所致出血。21世纪的坏血病]

[Haemorrhages due to vitamin C deficiency. Scurvy in the 21st century].

作者信息

Michiels Maykel, Mellema Marieke, Peters Frank P J

机构信息

Orbis Medisch Centrum, Afd. Interne geneeskunde, Sittard-Geleen, the Netherlands.

出版信息

Ned Tijdschr Geneeskd. 2010;154:A1638.

PMID:20699018
Abstract

A 68-year-old female with an extensive history of unexplained problems presented at the Department of Internal Medicine for an analysis of painful cutaneous abnormalities of the lower legs. A systemic cause could not be found. Later on the general practitioner noted haematoma and petechiae and subsequently a hypovitaminosis C. The patient received active vitamin C supplement for this. The cutaneous abnormalities on the legs had significantly improved after 3 weeks. This patient was found to have symptomatic hypovitaminosis C, also known as scurvy, as a complication of an psychiatric disorder. Although scurvy might appear to be a disease of the past that rarely occurs nowadays, it should nevertheless be given due consideration. This requires a good history taking.

摘要

一名68岁女性,有大量不明原因问题的病史,因小腿疼痛性皮肤异常到内科就诊。未发现系统性病因。后来全科医生注意到有血肿和瘀点,随后诊断为维生素C缺乏症。患者为此接受了活性维生素C补充剂治疗。3周后腿部的皮肤异常有明显改善。该患者被发现患有症状性维生素C缺乏症,也称为坏血病,是一种精神疾病的并发症。尽管坏血病似乎是一种过去的疾病,如今很少发生,但仍应予以充分考虑。这需要详细的病史采集。

相似文献

1
[Haemorrhages due to vitamin C deficiency. Scurvy in the 21st century].[维生素C缺乏所致出血。21世纪的坏血病]
Ned Tijdschr Geneeskd. 2010;154:A1638.
2
Scurvy masquerading as leukocytoclastic vasculitis: a case report and review of the literature.伪装成白细胞破碎性血管炎的坏血病:一例报告并文献复习
Cutis. 2005 Oct;76(4):261-6.
3
A case of scurvy in Singapore in the year 2006.2006年新加坡的一例坏血病病例。
Singapore Med J. 2007 Dec;48(12):1151-5.
4
Vitamin C deficiency in an elderly adult.一名老年成年人的维生素C缺乏症
J Am Geriatr Soc. 2013 Apr;61(4):657-8. doi: 10.1111/jgs.12183.
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A case of vascular purpura with scurvy.一例伴有坏血病的血管性紫癜。
Recenti Prog Med. 1992 Nov;83(11):652-3.
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Gingival hypertrophy: a solitary manifestation of scurvy.牙龈肥大:坏血病的一种单独表现。
Am J Otolaryngol. 2008 Nov-Dec;29(6):426-8. doi: 10.1016/j.amjoto.2007.11.006. Epub 2008 Jun 16.
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Identification and treatment of scurvy: a case report.坏血病的识别与治疗:一例病例报告
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005 Dec;100(6):688-92. doi: 10.1016/j.tripleo.2005.04.023. Epub 2005 Sep 26.
8
[Compartment syndrome of the legs and scurvy].[腿部骨筋膜室综合征与坏血病]
Can J Surg. 1988 Jan;31(1):65-6.
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Do you remember scurvy?你还记得坏血病吗?
Clin Ter. 2014;165(5):253-6. doi: 10.7417/CT.2014.1755.
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Unexpected Cause of Bleeding.出血的意外原因。
Am J Med. 2017 Sep;130(9):e387-e388. doi: 10.1016/j.amjmed.2017.03.016. Epub 2017 Apr 4.

引用本文的文献

1
Vitamins C and E: beneficial effects from a mechanistic perspective.维生素 C 和 E:从机制角度看有益作用。
Free Radic Biol Med. 2011 Sep 1;51(5):1000-13. doi: 10.1016/j.freeradbiomed.2011.05.017. Epub 2011 May 25.