Manciuc Carmen, Dorobăţ Carmen, Filip-Ciubotaru Florina-Mihaela
Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi Facultatea de Medicină, Disciplina Boli Infecţioase.
Rev Med Chir Soc Med Nat Iasi. 2010 Apr-Jun;114(2):327-31.
Viral hepatitis is a serious health problem all over the world. The aim of the study is to present the actual achievements in the therapeutically field and the general knowledge concerning the subject. Are presented the etiological agents of the acute and chronic hepatitis with the focus on hepatitis B and C, which has become a priority of WHO, with an incidence of the diseases of 360 billion/year for hepatitis B and an sub estimated level for C hepatitis. The most used drugs are presented and the therapeutical combination meant to decrease biological and virusological markers (ALAT, viral load) and to ameliorate the histological aspects of the liver. In conclusion, acute and chronic viral hepatitis represents a challenge for epidemiologists who try to stop the spread of the disease, but also for the infectious diseases specialists and gastroenterologists.
病毒性肝炎是全球一个严重的健康问题。本研究的目的是介绍治疗领域的实际成果以及关于该主题的一般知识。文中介绍了急慢性肝炎的病原体，重点是乙型和丙型肝炎，这已成为世界卫生组织的优先事项，乙型肝炎的发病率为每年3600亿例，丙型肝炎的发病率估计较低。文中介绍了最常用的药物以及旨在降低生物学和病毒学指标（谷丙转氨酶、病毒载量）并改善肝脏组织学状况的治疗组合。总之，急慢性病毒性肝炎对试图阻止疾病传播的流行病学家来说是一个挑战，对传染病专家和胃肠病学家来说也是如此。
