Stănescu D, Mihalache Doina, Irimescu O, Buciu Alina, Nistor Alina
Universităţii de Medicină şi Farmacie Gr.T. Popa Iaşi.
Rev Med Chir Soc Med Nat Iasi. 2010 Apr-Jun;114(2):372-5.
The aim of this study was to identify prognostic factors for morbidity, mortality and long term outcome and to analyze the different management modalities for acute diffuse peritonitis.
A clinical retrospective study was carried out on a series of 317 cases with acute peritonitis; admitted in the General Surgery Department, Hospital of Suceava, between 2006-2009.
There were 212 men (67%) and 105 women (33%) aged between 1 and 89 years. Preoperative concomitant disease was present in 31% of patients: cardiac disease was most common. The most common etiology was acute appendicitis in children 74 of cases (27.6%). Overall, 44 patients died during hospitalization. The cause of death was sepsis and multiple organ failure in 30 patients; malignancy in 8 patients and cardiac failure in 6 patients. Source control at the initial operation was possible in 282 of the patients (89%), of those 28 patients (9%) needed re-intervention. In 32 patients (10%), source control was not possible at the initial operation.
This study emphasis the importance of prompt surgical treatment and shows the impact of adapting antibiotic treatment.
本研究的目的是确定发病、死亡和长期预后的预后因素，并分析急性弥漫性腹膜炎的不同治疗方式。
对2006年至2009年间在苏恰瓦医院普通外科收治的317例急性腹膜炎患者进行了临床回顾性研究。
共有212名男性（67%）和105名女性（33%），年龄在1至89岁之间。31%的患者术前存在合并症：心脏病最为常见。最常见的病因是儿童急性阑尾炎，共74例（27.6%）。总体而言，44例患者在住院期间死亡。死亡原因是30例患者的败血症和多器官功能衰竭；8例患者为恶性肿瘤，6例患者为心力衰竭。282例患者（89%）在初次手术时实现了源头控制，其中28例（9%）需要再次干预。32例患者（10%）在初次手术时无法实现源头控制。
本研究强调了及时手术治疗的重要性，并显示了调整抗生素治疗的影响。
