Department of Obstetrics and Gynecology, Faculty of Medicine, University of Ufuk, Ankara, Turkey.
Fertil Steril. 2011 Jan;95(1):310-3. doi: 10.1016/j.fertnstert.2010.06.092. Epub 2010 Aug 11.
The aim of this study was to evaluate ischemia-modified albumin levels (IMA) in polycystic ovary syndrome (PCOS) cases with and without insulin resistance and the correlation of IMA with carotid intima media thickness, homocysteine, and high-sensitivity C-reactive protein levels. Significantly higher levels of IMA in young lean PCOS cases, more relevant in insulin resistant cases, indicates chronic hypoxia and oxidative stress which might play a role in the metabolic consequences in PCOS.
本研究旨在评估伴有和不伴有胰岛素抵抗的多囊卵巢综合征（PCOS）患者的缺血修饰白蛋白（IMA）水平，以及 IMA 与颈动脉内膜中层厚度、同型半胱氨酸和高敏 C 反应蛋白水平的相关性。年轻消瘦的 PCOS 患者的 IMA 水平显著升高，在胰岛素抵抗患者中更为相关，表明存在慢性缺氧和氧化应激，这可能在 PCOS 的代谢后果中起作用。
