Ji Geng-Zhong, Deng Fang-Ming, Wu Xin-Yin, Li Qing-Xiang, Song Jian-Hui, Li Wen-Hai, Yin Fei
Department of Pediatrics, Xiangya Hospital, Central South University, Changsha 410008, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2010 Aug;12(8):645-9.
To investigate blood lead levels (BLLs) and influencing factors of BLLs among preschool children living in towns of Hunan Province.
A total of 2 044 preschool children (1,108 boys and 936 girls) from towns of 12 regions in Hunan Province were enrolled by a cluster sampling between September 2008 and June 2009. The average age of the children was 4.4 ± 1.1 years (range 2 to 6 years). BLLs were determined using the atomic absorption spectrographic method. The influencing factors of BLLs were investigated using a standard questionnaire and logistic regression analysis.
The mean BLLs of the children were 81.9 ± 34.5 μg/L. BLLs more than 100 μg/ L were noted in 482 children (23.58%). Of the 482 children, 472 (23.09%) showed BLLs of 100-199 μg/L and 10 (0.49%) showed BLLs ≥ 200 μg/L. There were significant differences in the prevalence of elevated BLLs (≥ 100 μg/L) among different age groups (P < 0.01). The prevalence of elevated BLLs in boys (28.99%) was significantly higher than that in girls (21.98%) (P < 0.01). There were significant differences in the prevalence of elevated BLLs in children from different regions (P < 0.01). The logistic regression analysis showed that the male (OR = 1.449, P < 0.01), father's occupational lead exposure (OR = 1.314, P < 0.01)and maternal frequent use of hair dyes (OR = 1.678, P < 0.05) were risk factor for elevated BLLs.
The prevalence of elevated BLLs is higher in preschool children living in towns of Hunan Province and is associated with a child's region and age. The male, father's occupational lead exposure and maternal frequent use of hair dyes are risk factor for elevated BLLs.
调查湖南省城镇学龄前儿童的血铅水平(BLLs)及其影响因素。
2008年9月至2009年6月,采用整群抽样法,选取湖南省12个地区城镇的2044名学龄前儿童(男1108名,女936名)。儿童平均年龄为4.4±1.1岁(范围2至6岁)。采用原子吸收光谱法测定血铅水平。通过标准问卷和逻辑回归分析调查血铅水平的影响因素。
儿童血铅水平均值为81.9±34.5μg/L。482名儿童(23.58%)血铅水平超过100μg/L。在这482名儿童中,472名(23.09%)血铅水平为100 - 199μg/L,10名(0.49%)血铅水平≥200μg/L。不同年龄组血铅水平升高(≥100μg/L)的患病率存在显著差异(P < 0.01)。男孩血铅水平升高的患病率(28.99%)显著高于女孩(21.98%)(P < 0.01)。不同地区儿童血铅水平升高的患病率存在显著差异(P < 0.01)。逻辑回归分析显示,男性(OR = 1.449,P < 0.01)、父亲职业性铅暴露(OR = 1.314,P < 0.01)和母亲频繁使用染发剂(OR = 1.678,P < 0.05)是血铅水平升高的危险因素。
湖南省城镇学龄前儿童血铅水平升高的患病率较高,且与儿童所在地区和年龄有关。男性、父亲职业性铅暴露和母亲频繁使用染发剂是血铅水平升高的危险因素。