Milford C A, O'Flynn P E
ENT Department, Charing Cross Hospital, London, UK.
Clin Otolaryngol Allied Sci. 1991 Apr;16(2):160-2. doi: 10.1111/j.1365-2273.1991.tb01968.x.
Eight patients with a verrucous carcinoma of the larynx have been seen at the Charing Cross Hospital between 1970 and 1985. Seven patients were treated by primary radiotherapy and one by primary endoscopic laser excision. Four of those treated with radiotherapy developed recurrent disease which was treated by radical surgery in three and by endoscopic laser excision in one. The place of radiotherapy in the management of this condition requires further evaluation in view of the high rate of recurrence. Endoscopic laser excision may be a reasonable alternative to more radical surgery in this highly differentiated neoplasm.
1970年至1985年间,查令十字医院共收治了8例喉疣状癌患者。7例患者接受了原发性放射治疗,1例接受了原发性内镜激光切除治疗。接受放射治疗的患者中有4例出现了复发性疾病,其中3例接受了根治性手术治疗,1例接受了内镜激光切除治疗。鉴于复发率较高,放射治疗在这种疾病管理中的地位需要进一步评估。对于这种高分化肿瘤,内镜激光切除可能是一种比更激进手术更合理的替代方法。