Department of Plastic and Reconstructive Surgery, University Magna Graecia of Catanzaro, Italy.
Eur Rev Med Pharmacol Sci. 2010 Jul;14(7):639-42.
We present a clinical case of Melkersson-Rosenthal (M-R) syndrome associated with Down syndrome. No evidence of this association is described in the literature. We also present a technique for the macrocheilia treatment of lower lip caused by M-R syndrome in a patient with Down syndrome. This patient during pediatric age had many events of facial nerve paralysis and edematous episodes of lower lip with unknown etiology. This technique is based on a wedge full thickness central excision of the lower lip and on a transversal lozenge excision in the vermilion portion with orbicular muscle to reverse the chin-labial corner. The results are an agreeable aspect of the lip and physiological digestive and phonetic processes. The technique is safe and simple and the aesthetic functional result is very good. In our case, the postoperative complication is caused by an insufficient collaboration of the patient and it is solved in three weeks.
我们呈现了一例与唐氏综合征相关的梅尔基奥尔-罗森塔尔（M-R）综合征的临床病例。文献中并未描述这种关联。我们还介绍了一种针对唐氏综合征患者 M-R 综合征引起的巨唇的下唇治疗技术。该患者在儿童时期多次发生面神经麻痹和下唇水肿，病因不明。该技术基于下唇全厚楔形中央切除术和唇红部横菱形切除术，同时切除口轮匝肌以反转颏唇角。结果是唇部外观令人满意，且具有正常的消化和发音功能。该技术安全简单，美学和功能效果非常好。在我们的病例中，术后并发症是由于患者合作不足引起的，三周后得到解决。
