Bioacoustics Research Laboratory, Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, 405 North Mathews, Urbana, Illinois 61801, USA.
J Acoust Soc Am. 2010 Aug;128(2):903-8. doi: 10.1121/1.3460109.
Applicability of ultrasound phantoms to biological tissue has been limited because most phantoms have generally used strong scatterers. The objective was to develop very weakly scattering phantoms, whose acoustic scattering properties are likely closer to those of tissues and then compare theoretical simulations and experimental backscatter coefficient (BSC) results. The phantoms consisted of agar spheres of various diameters (nominally between 90 and 212 microm), containing ultrafiltered milk, suspended in an agar background. BSC estimates were performed at two institutions over the frequency range 1-13 MHz, and compared to three models. Excellent agreement was shown between the two laboratory results as well as with the three models.
超声仿体在生物组织中的应用受到限制,因为大多数仿体通常使用强散射体。本研究的目的是开发具有极低散射特性的仿体,其声学散射特性可能更接近组织的特性,然后比较理论模拟和实验反向散射系数(BSC)的结果。仿体由含有超滤液的牛奶的琼脂球组成,琼脂球的直径不同(名义上在 90 到 212 微米之间),悬浮在琼脂背景中。在两个机构的频率范围内 1-13 MHz 进行了 BSC 估计,并与三个模型进行了比较。两个实验室的结果以及与三个模型的结果之间都显示出极好的一致性。