Foletti Alberto, Ledda Mario, De Carlo Flavia, Grimaldi Settimio, Lisi Antonella
BITitalia, Milan, Italy.
Electromagn Biol Med. 2010 Aug;29(3):63-71. doi: 10.3109/15368378.2010.482480.
The aim of this work is the study of the effect of electromagnetic radiations (ELF-EMF) tuned to the calcium cyclotron resonance condition of 7.0 Hz, 9.2 microT on the differentiation process of pituitary corticotrope-derived AtT20 D16V cells. These cells respond to nerve growth factor by extending neurite-like processes. To establish whether exposure to the field could influence the molecular biology of the pituitary gland, a corticotrope-derived cells line (AtT20 D16V) was exposed to ELF-EMF at a frequency of 7.0 Hz, 9.2 microT electromagnetic field by a Vega Select 719 power supply. Significant evidence was obtained to conclude that as little as 36 h exposure to the Ca(2+) ICR condition results in enhanced neurite outgrowth, with early expression and aggregation of the neuronal differentiation protein NF-200 into neurite structures.
本研究的目的是探讨调谐至7.0 Hz、9.2微特斯拉钙回旋共振条件的电磁辐射（极低频电磁场，ELF-EMF）对垂体促肾上腺皮质激素细胞来源的AtT20 D16V细胞分化过程的影响。这些细胞通过延伸神经突样突起对神经生长因子作出反应。为了确定暴露于该场是否会影响垂体的分子生物学，使用Vega Select 719电源将一种促肾上腺皮质激素细胞系（AtT20 D16V）暴露于频率为7.0 Hz、9.2微特斯拉的极低频电磁场中。有重要证据表明，暴露于Ca(2+) ICR条件下仅36小时就会导致神经突生长增强，神经元分化蛋白NF-200在神经突结构中早期表达并聚集。
