Department of Neurosurgery and Oncology, Johns Hopkins Hospital, Phipps Building, Room 118, Baltimore, Maryland 21287, USA.
J Clin Neurosci. 2010 Nov;17(11):1423-7. doi: 10.1016/j.jocn.2010.04.013. Epub 2010 Aug 13.
Juvenile nasopharyngeal angiofibromas (JNAs) are rare vascular tumors which arise in the nasopharynx of adolescent males. Patients with these tumors can be cured by surgery, which is the treatment of choice in the majority of patients. Traditional surgical techniques for patients with JNAs have been via open surgical approaches. Since 2000, however, the surgical management of JNAs has changed due to advances in endoscopic procedures and such approaches are standard for early stage lesions which are limited to the nasal cavity, nasopharynx and the paranasal sinuses. The role and limitations of endoscopic approaches for JNAs with skull base and intracranial involvement are being defined. In this report, we describe a patient with a JNA with skull base involvement who underwent an expanded endonasal endoscopic approach for a complete resection. Additionally, we review the literature of endoscopic approaches to JNAs with skull base involvement.
青少年鼻咽血管纤维瘤（JNAs）是一种罕见的血管肿瘤，发生在青少年男性的鼻咽部。这些肿瘤的患者可以通过手术治愈，手术是大多数患者的首选治疗方法。传统上，对于 JNAs 患者的手术治疗方法是通过开放式手术进行的。然而，自 2000 年以来，由于内窥镜手术技术的进步，JNA 的手术治疗方法发生了变化，这些方法已成为局限于鼻腔、鼻咽和鼻窦的早期病变的标准治疗方法。目前正在确定内窥镜方法在涉及颅底和颅内的 JNAs 中的作用和局限性。在本报告中，我们描述了一名患有颅底受累 JNA 的患者，他接受了扩大经鼻内镜手术以实现完全切除。此外，我们还回顾了涉及颅底受累的 JNAs 的内窥镜方法的文献。
