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中文儿童白内障患者的视力障碍和手术就诊延迟。

Visual impairment and delay in presentation for surgery in chinese pediatric patients with cataract.

机构信息

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.

出版信息

Ophthalmology. 2011 Jan;118(1):17-23. doi: 10.1016/j.ophtha.2010.04.014. Epub 2010 Aug 14.

Abstract

PURPOSE

To report visual impairment and blindness and delay in presentation for surgery in Chinese pediatric patients with cataract.

DESIGN

Retrospective case series.

PARTICIPANTS

A total of 196 children (309 eyes) with congenital or developmental cataract.

METHODS

Surgery was performed in all patients. Visual impairment and blindness were defined as best-corrected visual acuity < 20/60. The characteristics, visual acuity, and time delay to surgery of these children were evaluated.

MAIN OUTCOME MEASURES

Incidence of visual impairment and blindness, ages at disease recognition and at surgery, and duration of delay in presentation for surgery.

RESULTS

Visual acuity was 20/25 or better in 22 eyes (7.1%), between 20/25 and 20/40 in 72 eyes (23.3%), and between 20/40 and 20/60 in 87 eyes (28.2%). Visual impairment and blindness occurred in 41.4% of eyes, 52.0% of patients, 35.4% of patients with bilateral cataract, and 74.7% of patients with unilateral cataract. The frequency of visual impairment and blindness in eyes with combined nystagmus, combined strabismus, total cataract, nuclear cataract, and posterior polar cataract was 84.4%, 75%, 63.8%, 48%, and 48.3%, respectively. Severe postoperative complications resulted in 14.8% of visual impairment and blindness. The mean ages at disease recognition and at surgery were 22.6 ± 30.4 months and 68.3 ± 40.0 months, respectively. The mean delay of presentation for surgery was 49.6 ± 39.8 months in all patients and 35.7 ± 32.2 months in the patients with congenital cataract. The disease was recognized within 6 months of age in 46 children (40.7%) with bilateral cataract and 10 children (12.0%) with unilateral cataract. Among these children, only 18 (15.9%) with bilateral cataract and 1 (1.2%) with unilateral cataract underwent surgery between 3 and 6 months of age. No patients received surgical intervention within 3 months.

CONCLUSIONS

Severe visual impairment is common in pediatric patients with cataract in China. Delayed presentation to the hospital and late surgical treatment are the major reasons and deserve greater attention.

摘要

目的

报告中国小儿白内障患者的视力损害和失明以及手术延误情况。

设计

回顾性病例系列。

参与者

共有 196 名儿童(309 只眼)患有先天性或发育性白内障。

方法

所有患者均进行手术。视力损害和失明定义为最佳矫正视力<20/60。评估这些儿童的特征、视力和手术延误时间。

主要观察指标

视力损害和失明的发生率、疾病发现和手术的年龄以及手术延误时间。

结果

22 只眼(7.1%)的视力为 20/25 或更好,72 只眼(23.3%)的视力为 20/25 至 20/40,87 只眼(28.2%)的视力为 20/40 至 20/60。41.4%的眼、52.0%的患者、35.4%的双侧白内障患者和 74.7%的单侧白内障患者出现视力损害和失明。伴有眼球震颤、斜视、完全白内障、核性白内障和后极性白内障的眼视力损害和失明的发生率分别为 84.4%、75.0%、63.8%、48.0%和 48.3%。严重的术后并发症导致 14.8%的眼视力损害和失明。疾病发现和手术的平均年龄分别为 22.6±30.4 个月和 68.3±40.0 个月。所有患者的平均手术延误时间为 49.6±39.8 个月,先天性白内障患者的平均手术延误时间为 35.7±32.2 个月。46 名双侧白内障患儿(40.7%)和 10 名单侧白内障患儿(12.0%)在 6 个月龄内发现疾病。在这些儿童中,仅有 18 名双侧白内障患儿(15.9%)和 1 名单侧白内障患儿(1.2%)在 3 至 6 个月龄时接受了手术。没有患儿在 3 个月内接受手术干预。

结论

中国小儿白内障患者视力损害严重,就诊延迟和手术治疗延迟是主要原因,值得高度关注。

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