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老年人冻结步态:相关疾病、临床特征、评估与治疗。

Freezing of gait in older people: associated conditions, clinical aspects, assessment and treatment.

机构信息

South Warwickshire General Hospital, Lakin Road, Warwick CV34 5BW, UK.

出版信息

Postgrad Med J. 2010 Aug;86(1018):472-7. doi: 10.1136/pgmj.2009.090456.

Abstract

Freezing of gait (FOG) is a disabling condition in older people. It is common in Parkinson's disease (PD) and other parkinsonian syndromes. The assessment of this condition poses challenges due to its episodic and transient nature and its frequent association with cognitive impairment. The pathophysiology of FOG is complex and poorly understood. Morphological brain imaging is of limited value in the evaluation of FOG, and functional imaging techniques are currently being developed to study the phenomenon. The treatment of 'off' time FOG in PD is relatively straight forward, but 'on' freezing in PD and FOG associated with other conditions may be difficult to treat. FOG is a strong risk factor for falls and adversely affects the quality of life of patients and carers. A multidisciplinary team approach is essential for optimum management.

摘要

冻结步态(FOG)是老年人的一种致残状况。它在帕金森病(PD)和其他帕金森综合征中很常见。由于其间歇性和短暂性以及经常与认知障碍相关,因此评估此病症具有挑战性。FOG 的病理生理学很复杂,目前了解甚少。形态脑影像学在评估 FOG 方面的价值有限,目前正在开发功能成像技术来研究该现象。PD 中的“关”期 FOG 的治疗相对简单,但 PD 中的“开”期冻结和与其他病症相关的 FOG 可能难以治疗。FOG 是跌倒的一个强烈危险因素,并对患者和护理人员的生活质量产生不利影响。多学科团队方法对于最佳管理至关重要。

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