Valencia University Medical and Dental School, Valencia, Spain.
Med Oral Patol Oral Cir Bucal. 2011 Jul 1;16(4):e541-5. doi: 10.4317/medoral.16.e541.
This study was conducted to determine the hemodynamic and ventilatory changes during implant surgery with intravenous conscious sedation, and whether preoperative anxiety, gender or age influence these parameters.
A prospective study carried out between May 2004 and February 2007, on 102 patients treated with dental implants under local anesthesia and conscious intravenous sedation. Patients completed a questionnaire prior to surgery to evaluate preoperative dental anxiety using Corah's scale. The hemodynamic and ventilatory changes were evaluated by monitoring systolic pressure (SP), diastolic pressure (DP), heart rate (HR) and oxygen saturation (SaO2). These values were collected at 5 points during surgery; before commencing the operation (baseline value), during local anesthetic injection, at the moment of incision and raising of a mucoperiosteal flap, during implant placement, and finally at suturing. Intravenous conscious sedation was administered between baseline value and injection of the local anesthetic.
The highest SP and DP were recorded at baseline and at suturing. The highest HR was recorded at the moment of incision and raising of the mucoperiosteal flap; the lowest SaO2 was recorded at local anesthetic injection. There was no relationship between hemodynamic and ventilatory values and preoperative anxiety or gender. A greater age was associated with higher SP and lower SaO2, these differences being statistically significant.
Most of the cardiovascular and ventilatory changes induced by the implant surgery with intravenous conscious sedation were within normal ranges. The results indicate that midazolam with fentanyl do not produce important hemodynamic and ventilatory changes, being a good association for intravenous conscious sedation in dental implant surgery.
本研究旨在确定静脉内清醒镇静下种植手术过程中的血液动力学和通气变化,以及术前焦虑、性别或年龄是否会影响这些参数。
这是一项于 2004 年 5 月至 2007 年 2 月进行的前瞻性研究,共纳入 102 例在局部麻醉和静脉内清醒镇静下接受牙种植治疗的患者。患者在手术前完成一份问卷,使用 Corah 量表评估术前的牙科焦虑程度。通过监测收缩压(SP)、舒张压(DP)、心率(HR)和血氧饱和度(SaO2)来评估血液动力学和通气变化。这些值在手术期间的 5 个时间点采集,分别为手术开始前(基线值)、局部麻醉注射时、切开和掀起黏骨膜瓣时、植入物放置时,以及最后缝合时。静脉内清醒镇静在基线值和局部麻醉注射之间给予。
SP 和 DP 的最高值记录在基线值和缝合时,HR 的最高值记录在切开和掀起黏骨膜瓣时,SaO2 的最低值记录在局部麻醉注射时。血液动力学和通气值与术前焦虑或性别之间没有关系。年龄越大,SP 越高,SaO2 越低,这些差异具有统计学意义。
静脉内清醒镇静下种植手术引起的大多数心血管和通气变化都在正常范围内。结果表明,咪达唑仑联合芬太尼不会产生重要的血液动力学和通气变化,是牙种植手术中静脉内清醒镇静的良好选择。