Hong Yeon Ju, Oh Ji Eun, Choi You Won, Myung Ki Bum, Choi Hae Young
Department of Dermatology, School of Medicine, Ewha Womans University, Seoul, Korea.
Ann Dermatol. 2010 Aug;22(3):330-2. doi: 10.5021/ad.2010.22.3.330. Epub 2010 Aug 5.
Eccrine porocarcinoma (EP) is a rare malignant tumor arising from the intraepidermal eccrine duct. The tumor cells frequently contain glycogen, but prominent clear cell changes in EP are rarely reported. A 78-year-old woman presented with a slightly pruritic, erythematous, verrucous plaque on her left thigh. Histopathological examination revealed intraepidermal tumor cell nests composed of small basaloid cells and duct-like structures lined by periodic acid-Schiff (PAS)-positive cuticles. Besides the typical findings of EP, clear cell changes were predominantly observed in the tumor cell aggregations. Herein we report a case of the clear cell variant of EP rarely reported in previous literature.
小汗腺癌（EP）是一种起源于表皮内小汗腺导管的罕见恶性肿瘤。肿瘤细胞常含有糖原，但小汗腺癌中显著的透明细胞改变鲜有报道。一名78岁女性患者左大腿出现轻度瘙痒的红斑性疣状斑块。组织病理学检查显示，表皮内肿瘤细胞巢由小的基底样细胞和内衬过碘酸-希夫（PAS）阳性角质层的导管样结构组成。除了小汗腺癌的典型表现外，在肿瘤细胞聚集体中主要观察到透明细胞改变。在此，我们报告一例先前文献中很少报道的小汗腺癌透明细胞变体病例。
