与西酞普兰使用相关的抗利尿激素分泌不当综合征（SIADH）。
Syndrome of inappropriate ADH secretion (SIADH) associated with citalopram use.
机构信息
Consultant Psychiatrist, Kirpekar Hospital, Nagpur.
出版信息
Indian J Psychiatry. 2005 Apr;47(2):119-20. doi: 10.4103/0019-5545.55960.
Abstract
Selective serotonin reuptake inhibitors (SSRIs) can cause the syndrome of inappropriate antidiuretic hormone secretion (SIADH). SIADH is associated with hyponatraemia without oedema. We report the case of a patient who developed acute-onset hyponatraemia that progressed rapidly to serious neurological dysfunction shortly after the introduction of citalopram. All SSRIs including citalopram should be used with care in the elderly. The water and electrolyte balance should be monitored carefully during SSRI therapy.
摘要
选择性 5-羟色胺再摄取抑制剂（SSRIs）可引起抗利尿激素分泌不当综合征（SIADH）。SIADH 与无水肿的低钠血症有关。我们报告了一例患者的病例，在引入西酞普兰后不久，该患者迅速发生急性低钠血症，并迅速发展为严重的神经功能障碍。所有包括西酞普兰在内的 SSRIs 在老年人中都应谨慎使用。在 SSRI 治疗期间应密切监测水和电解质平衡。
相似文献
1
Syndrome of inappropriate ADH secretion (SIADH) associated with citalopram use.
Indian J Psychiatry. 2005 Apr;47(2):119-20. doi: 10.4103/0019-5545.55960.
2
Incidence of selective serotonin reuptake inhibitor (SSRI) induced hyponatraemia due to the syndrome of inappropriate antidiuretic hormone (SIADH) secretion in the elderly.
Int J Geriatr Psychiatry. 1998 Jan;13(1):12-5.
3
Escitalopram Induced SIADH in an Elderly Female: A Case Study.
Psychopharmacol Bull. 2017 Sep 15;47(4):64-67.
4
Syndrome of inappropriate secretion of antidiuretic hormone due to citalopram and venlafaxine.
Gen Hosp Psychiatry. 2007 Jan-Feb;29(1):81-4. doi: 10.1016/j.genhosppsych.2006.11.001.
5
Syndrome of inappropriate antidiuretic hormone associated with escitalopram therapy.
CNS Spectr. 2006 Jun;11(6):429-32. doi: 10.1017/s1092852900014620.
6
Citalopram-induced SIADH in a hypertensive patient on salt restricted diet.
J Psychopharmacol. 2007 Aug;21(6):665-7. doi: 10.1177/0269881106073596. Epub 2006 Nov 8.
7
Severe symptomatic hyponatremia during citalopram therapy.
Am J Med Sci. 2001 Feb;321(2):159-60. doi: 10.1097/00000441-200102000-00009.
8
Syndrome of inappropriate antidiuretic hormone secretion: a story of duloxetine-induced hyponatraemia.
BMJ Case Rep. 2015 Apr 24;2015:bcr2014208037. doi: 10.1136/bcr-2014-208037.
9
Citalopram-induced severe hyponatraemia with coma and seizure. Case report with literature and spontaneous reports review.
Adverse Drug React Toxicol Rev. 2002;21(4):179-87. doi: 10.1007/BF03256195.
10
Hyponatremia and antidiuresis syndrome.
Ann Endocrinol (Paris). 2011 Dec;72(6):500-12. doi: 10.1016/j.ando.2011.10.001. Epub 2011 Nov 25.
引用本文的文献
1
Possible Biological Mechanisms Linking Mental Health and Heat-A Contemplative Review.
Int J Environ Res Public Health. 2018 Jul 18;15(7):1515. doi: 10.3390/ijerph15071515.
2
Severe hyponatremia associated with escitalopram.
J Family Med Prim Care. 2017 Apr-Jun;6(2):453-454. doi: 10.4103/2249-4863.220043.
3
Confusion after starting citalopram in a renal transplant patient.
BMJ Case Rep. 2013 Jul 9;2013:bcr2013010511. doi: 10.1136/bcr-2013-010511.
4
Research on antidepressants in India.
Indian J Psychiatry. 2010 Jan;52(Suppl 1):S341-54. doi: 10.4103/0019-5545.69263.
本文引用的文献
1
Overview of the safety of citalopram.
Psychopharmacol Bull. 2003 Winter;37(1):96-121.
2
Citalopram-induced severe hyponatraemia with coma and seizure. Case report with literature and spontaneous reports review.
Adverse Drug React Toxicol Rev. 2002;21(4):179-87. doi: 10.1007/BF03256195.
3
Citalopram-associated SIADH.
Ann Pharmacother. 2002 Oct;36(10):1558-63. doi: 10.1345/aph.1C071.
4
A case of SIADH and hyponatremia associated with citalopram.
Psychosomatics. 2002 May-Jun;43(3):241-2. doi: 10.1176/appi.psy.43.3.241.
5
Hyponatraemia in elderly psychiatric patients treated with Selective Serotonin Reuptake Inhibitors and venlafaxine: a retrospective controlled study in an inpatient unit.
Int J Geriatr Psychiatry. 2002 Mar;17(3):231-7. doi: 10.1002/gps.591.
6
SSRI-induced SIADH in older people.
J Am Geriatr Soc. 1999 May;47(5):630-1. doi: 10.1111/j.1532-5415.1999.tb02584.x.
7
Incidence of selective serotonin reuptake inhibitor (SSRI) induced hyponatraemia due to the syndrome of inappropriate antidiuretic hormone (SIADH) secretion in the elderly.
Int J Geriatr Psychiatry. 1998 Jan;13(1):12-5.
Zotero 插件