重症监护患者中心钠素肽的解读：它是否会有用？
The interpretation of brain natriuretic peptide in critical care patients; will it ever be useful?
机构信息
General Intensive Care, St George's Hospital NHS Trust, Cranmer Terrace, London SW17 0QT, UK.
出版信息
Crit Care. 2010;14(4):184. doi: 10.1186/cc9083. Epub 2010 Aug 6.
Abstract
The measurement of B-type natriuretic peptide (BNP) is recommended for the diagnosis of decompensated heart failure, the prognosis of chronic heart failure is worse if BNP is increased and studies suggest that BNP is useful to guide therapy. A study by Di Somma and colleagues adds to the body of evidence showing that patients with a marked decrease in BNP concentrations during their hospital admission are less likely to be readmitted with a further adverse cardiac event than patients in whom BNP fails to decrease. However, the wider interpretation of BNP concentrations in critically ill patients with other conditions remains uncertain.
摘要
B 型利钠肽（BNP）的测量被推荐用于心力衰竭失代偿的诊断，如果 BNP 升高，慢性心力衰竭的预后则更差，研究表明 BNP 有助于指导治疗。Di Somma 及其同事的研究进一步证明，在住院期间 BNP 浓度显著下降的患者，与 BNP 浓度未下降的患者相比，再次发生不良心脏事件的可能性更小。然而，在患有其他疾病的危重症患者中，对 BNP 浓度的更广泛解释仍不确定。
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