金沉积的红色、绿色和蓝色荧光硅纳米粒子的合成与表征及其在生物传感器中的应用。

Synthesis and characterization of gold-deposited red, green and blue fluorescent silica nanoparticles for biosensor application.

机构信息

Department of Chemical & Biomolecular Engineering (BK21 program) and Center for Ultramicrochemical Process Systems, KAIST, 335 Gwahangno, Yuseong-gu, Daejeon 305-701, Republic of Korea.

出版信息

Chem Commun (Camb). 2010 Sep 14;46(34):6374-6. doi: 10.1039/c0cc00762e. Epub 2010 Aug 12.

DOI:10.1039/c0cc00762e

PMID:20714531

Abstract

Fluorescent silica nanoparticles deposited with highly monodisperse gold nanoparticles (1-2 nm) were synthesized via the W/O method and intensive ultrasound irradiation. A large surface area of gold-doped fluorescent silica nanoparticle serves as a platform to immobilize a specific binding protein for biomolecules interaction in bioimaging applications.

摘要

通过 W/O 方法和强烈的超声辐射合成了沉积有高度单分散金纳米粒子（1-2nm）的荧光硅纳米粒子。金掺杂荧光硅纳米粒子的大表面积可用作平台，用于固定用于生物成像应用中生物分子相互作用的特定结合蛋白。