Westfälische Wilhelms-Universität Münster, Organisch-Chemisches Institut, Corrensstraße 40, 48149 Münster, Germany.
Angew Chem Int Ed Engl. 2010 Sep 17;49(39):6940-52. doi: 10.1002/anie.201001865.
Quantification and variation of characteristic properties of different ligand classes is an exciting and rewarding research field. N-Heterocyclic carbenes (NHCs) are of special interest since their electron richness and structure provide a unique class of ligands and organocatalysts. Consequently, they have found widespread application as ligands in transition-metal catalysis and organometallic chemistry, and as organocatalysts in their own right. Herein we provide an overview on physicochemical data (electronics, sterics, bond strength) of NHCs that are essential for the design, application, and mechanistic understanding of NHCs in catalysis.
定量和变化不同配体类别的特征性质是一个令人兴奋和有益的研究领域。N-杂环卡宾（NHCs）特别有趣，因为它们的电子丰富度和结构提供了一类独特的配体和有机催化剂。因此，它们已被广泛用作过渡金属催化和有机金属化学中的配体，以及本身的有机催化剂。在此，我们提供了 NHCs 的物理化学数据（电子、空间、键强度）概述，这些数据对于 NHCs 在催化中的设计、应用和机理理解至关重要。
