Hiramatsu Masayuki
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences/Laboratory of Neuropsychopharmacology, Graduate School of Environmental and Human Sciences, Meijo University.
Nihon Rinsho. 2010 Aug;68(8):1506-10.
The number of people dependent on opiate drugs, including heroin, is still high, and these abused drugs are major social issues, both in the social science and medically. The mechanisms of physical dependence and withdrawal symptoms in laboratory animals are becoming clear; however, no useful method to detoxify abusers with opioid dependence in clinical situation has been established, and alternative therapy with methadone, used in Europe and America, cannot be used in Japan. Here, I will outline the global trend of opium abuse, including heroin and morphine, and summarize the problems of heroin abuse.
依赖包括海洛因在内的阿片类药物的人数仍然居高不下，这些滥用药物在社会科学和医学领域都是重大的社会问题。实验动物中身体依赖和戒断症状的机制正逐渐明晰；然而，临床上尚未建立起有效的方法来帮助阿片类药物依赖者戒毒，而且欧美使用的美沙酮替代疗法在日本无法应用。在此，我将概述包括海洛因和吗啡在内的鸦片滥用的全球趋势，并总结海洛因滥用问题。
